Tratamentos psicodélicos na depressão: potencial terapêutico, desafios e caminhos futuros

Abstract

The present study explores the therapeutic potential of psychedelic substances, such as psilocybin and ayahuasca, in the treatment of depression, especially in cases where traditional methods have proven ineffective. The analysis covered the mechanisms of action of these substances, their effects on brain neurochemistry, and the subjective experiences associated with their use. Additionally, social and cultural barriers that limit the acceptance and therapeutic use of these treatments in Brazil were discussed. The results indicate that, despite the challenges, psychedelic treatments present significant potential for addressing depression, offering a new perspective that can complement or replace conventional treatments.