Intraosseous xanthoma of the mandible: a multi institutional case series with a literature review

Página do item simplificado
dc.creatorJosé Alcides Almeida de Arruda
dc.creatorBruno Augusto Benevenuto de Andrade
dc.creatorRicardo Alves de Mesquita
dc.creatorTatiana Fernandes Araújo Almeida
dc.creatorLucas Guimarães Abreu
dc.creatorMárcio Bruno Figueiredo do Amaral
dc.creatorAna Lia Anbinder
dc.creatorRené Martínez Flores
dc.creatorMichelle Agostini
dc.creatorMário José Romañach
dc.creatorTarcília Aparecida da Silva
dc.date.accessioned2025-04-09T19:39:46Z
dc.date.accessioned2025-09-09T00:38:15Z
dc.date.available2025-04-09T19:39:46Z
dc.date.issued2019
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/jop.12940
dc.identifier.issn1600-0714
dc.identifier.urihttps://hdl.handle.net/1843/81430
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Oral Pathology & Medicine
dc.rightsAcesso Restrito
dc.subjectJaw
dc.subjectMandible
dc.subjectXanthomatosis
dc.subjectRadiography
dc.subjectSpontaneous perforation
dc.subjectCD68 molecule
dc.subjectS100 proteins
dc.subjectCurettage
dc.subjectMandible
dc.subject.otherIntraosseous
dc.subject.otherJaw
dc.subject.otherMandible
dc.subject.otherXanthoma
dc.subject.otherXanthomatosis
dc.titleIntraosseous xanthoma of the mandible: a multi institutional case series with a literature review
dc.typeArtigo de periódico
local.citation.epage942
local.citation.issue10
local.citation.spage935
local.citation.volume48
local.description.resumoBackground: The aim of the present study was to report the clinicopathologic, radiographic and immunohistochemical features of five South American cases of intraosseous xanthomas of the mandible and to compare them to those detected in a literature review. Methods: Clinical data were collected from the records of three Oral and Maxillofacial Pathology services in South America and compared with those compiled from a literature review based on a search of three electronic databases (PubMed, Web of Science and Scopus). All cases were evaluated by haematoxylin and eosin staining and immunohistochemistry for CD68 and S-100. Results: The series comprised four females (80%) and one male (20%) with a mean age of 23.3 ± 10.9 years (range: 13-45 years). In four cases, there was involvement of the posterior region of the mandible (80%). The lesions presented radiographically as unilocular (60%) radiolucencies with punched-out margin (80%). All cases predominantly consisted of CD68-positive and S-100-negative xanthomatous cells. No recurrences were observed after curettage, with a median follow-up of 27 months. Conclusion: Intraosseous xanthoma of the jaws is a rare benign disorder. We report here five additional cases affecting the mandible, for a total of 36 cases of the jaws reported in the literature. Overall, this lesion has predilection for posterior sites of the mandible of asymptomatic young adults.
local.identifier.orcidhttps://orcid.org/0000-0002-6599-3950
local.identifier.orcidhttps://orcid.org/0000-0002-3259-606X
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.identifier.orcidhttps://orcid.org/0000-0002-3216-5649
local.identifier.orcidhttps://orcid.org/0000-0003-2258-8071
local.identifier.orcidhttps://orcid.org/0000-0003-0350-5170
local.identifier.orcidhttps://orcid.org/0000-0003-3930-4274
local.identifier.orcidhttps://orcid.org/0000-0002-0800-8117
local.identifier.orcidhttps://orcid.org/0000-0002-3648-337X
local.identifier.orcidhttps://orcid.org/0000-0002-7853-5916
local.identifier.orcidhttps://orcid.org/0000-0001-9623-7835
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.12940

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG