Bioactive activities and chemical profile characterization using paper spray mass spectrometry of extracts of Eriobotrya japonica Lindl. leaves

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dc.creatorViviane Dias Medeiros Silva
dc.creatorMaria Clara Coutinho Macedo
dc.creatorAmanda Neri dos Santos
dc.creatorMauro Ramalho Silva
dc.creatorRodinei Augusti
dc.creatorInayara Cristina Alves Lacerda
dc.creatorJúlio Onésio Ferreira Melo
dc.creatorCamila Argenta Fante
dc.date.accessioned2022-05-23T21:44:00Z
dc.date.accessioned2025-09-08T23:53:16Z
dc.date.available2022-05-23T21:44:00Z
dc.date.issued2020
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doi10.1002/rcm.8883
dc.identifier.issn0951-4198
dc.identifier.urihttps://hdl.handle.net/1843/41905
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRapid Communications in Mass Spectrometry
dc.rightsAcesso Restrito
dc.subjectEspectrometria de massas
dc.subjectPaper spray
dc.subjectEriobotrya japonica Lindl. leaves
dc.subject.otherEspectrometria de massas
dc.subject.otherPaper spray
dc.subject.otherEriobotrya japonica Lindl. leaves
dc.titleBioactive activities and chemical profile characterization using paper spray mass spectrometry of extracts of Eriobotrya japonica Lindl. leaves
dc.typeArtigo de periódico
local.citation.epage12
local.citation.issue19
local.citation.spage1
local.citation.volume34
local.description.resumoRationale The loquat (Eriobotrya japonica Lindl.) is a fruit tree that has been used in Chinese medicine for thousands of years for the treatment of various diseases. The loquat leaf extracts contain several bioactive compounds with antioxidant and antimicrobial properties, and identification of these substances using quick and simple methods has been an analytical trend. Methods The influence of dehydration of loquat leaves (without drying, at 40°C, and at 60°C), the type of solvent (ethanol and methanol), and the method of extraction (shaking and ultrasound) on obtaining extracts containing phenolic compounds and substances with antioxidant and antimicrobial properties was evaluated. The chemical constituents of an extract were identified using paper spray mass spectrometry (PS-MS). Results The extract obtained from the dehydrated leaves at 40°C presented the best results. The extracts obtained from these leaves and with ethanol had the highest values of total phenolics and antioxidant activities, but the methanolic extract subjected to ultrasound had the highest levels of chlorogenic, caffeic, and ellagic acids. All extracts evaluated inhibited the growth of Staphylococcus aureus. Using the PS-MS technique, it was possible to identify the presence of 49 substances such as organic acids, phenolic acids, flavonoids, sugars, quinones, and terpenes. Conclusions In general, extracts of dehydrated leaves at 40°C and extracted with ethanol using ultrasound can be considered a good source of bioactive compounds with potential applications as functional ingredients or additives in the food and pharmaceutical industries. PS-MS was demonstrated to be a simple and ultrafast technique to obtain the chemical profile of the loquat leaf extract.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.8883

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