Oral amyloidosis: an update
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Universidade Federal de Minas Gerais
Descrição
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Artigo de periódico
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Membros da banca
Resumo
Background
Amyloidosis is a disease characterized by the progressive deposition of abnormal proteins that can occur in any organ. In the oral cavity, the tongue is the most common affected site, usually causing macroglossia. Biopsy is essential for the diagnosis and the occurrence of its systemic form is mandatory to be investigated. This systematic review evaluated the existing information in the literature on Amyloidosis in the oral cavity to allow a more comprehensive and updated analysis of its clinicopathological characteristics, as well as to explore the main forms of treatment and prognostic factors.
Material and Methods
Electronic searches were undertaken in five databases supplemented by manual scrutiny.
Results
A total of 111 studies were included with 158 individuals.
Conclusions
The disease had a higher prevalence in women, the tongue was the most affected site, as well as the systemic form of the disease. The worst prognosis was for cases of systemic amyloidosis associated with multiple myeloma
Abstract
Assunto
Amyloidosis, Mouth, Congo red, Tongue, Proteins, Multiple myeloma, Prevalence, Prognosis, Therapeutics, Macroglossia, Diagnosis, Biopsy
Palavras-chave
Amyloidosis, mouth, Congo red, Proteins
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Endereço externo
https://pmc.ncbi.nlm.nih.gov/articles/PMC10314358/