Método de diagnóstico para infecção causada pelo Helicobacter pylori em crianças

Abstract

Helicobacter pylori is responsible for one of the most common chronic infections world wide. This bacterium is associated with several gastric disorders such as gastritis, peptic ulcer, gastric cancer and gastric MALT lymphoma. The infection is acquired predominantly in childhood and prevalence rates are higher among children in developing countries. The infection can be diagnosed by several invasive methods (culture, histology, urease test and PCR preformed) and noninvasive (urea breath test, antigen detection in stool samples and detection of anti-H. Pylori). It was aim of this study was to perform a literature review in order to evaluate the performance of different diagnostic methods for this infection. This study adopted as a methodological strategy integrative review of the national and international literature on the Diagnostic methods for Helicobacter pylori infection in children. We evaluated 70 articles and one book chapter, and found differences in sensitivity and specificity for each test used in children in this study, we concluded that no method has 100% sensitivity and specificity for the diagnosis of infection caused by H. pylori is therefore recommended at least two methods to diagnose this infection.