Exploring the structural landscape of 2-(thio­phen-2-yl)-1,3-benzo­thia­zole: high-Z′ packing polymorphism and cocrystallization with calix[4]tube

dc.creatorMeiry Edivirges Alvarenga
dc.creatorAna Karoline Silva Medanha Valdo
dc.creatorLeandro Ribeiro
dc.creatorJosé Antonio do Nascimento Neto
dc.creatorDébora Pereira Araújo
dc.creatorCleiton Moreira da Silva
dc.creatorÂngelo de Fátima
dc.creatorFelipe Terra Martins
dc.date.accessioned2024-10-09T16:44:16Z
dc.date.accessioned2025-09-09T00:12:40Z
dc.date.available2024-10-09T16:44:16Z
dc.date.issued2019
dc.identifier.doihttps://doi.org/10.1107/S2053229619005886
dc.identifier.issn2053-2296
dc.identifier.urihttps://hdl.handle.net/1843/77334
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofActa Crystallographica Section C: Structural Chemistry
dc.rightsAcesso Restrito
dc.subjectCalixarenos
dc.subjectCristais
dc.subjectPolimorfismo (Cristalografia)
dc.subjectTiazóis
dc.subject.otherPacking polymorphism
dc.subject.otherCrystal structure
dc.subject.otherCocrystal
dc.subject.otherCalix[4]tube
dc.subject.otherCalixarene
dc.subject.otherHigh Z
dc.subject.otherBenzo­thia­zole
dc.titleExploring the structural landscape of 2-(thio­phen-2-yl)-1,3-benzo­thia­zole: high-Z′ packing polymorphism and cocrystallization with calix[4]tube
dc.typeArtigo de periódico
local.citation.epage677
local.citation.spage667
local.citation.volume75
local.description.resumoWe report here for the first time a cocrystal of the so-called neutral calix[4]tube, which is two tail-to-tail-arranged and partially deprotonated tetrakis­(carb­oxy­meth­oxy)calix[4]arenes, including three sodium ions, with 2-(thio­phen-2-yl)-1,3-benzo­thia­zole, namely trisodium bis­(carb­oxy­meth­oxy)bis­(carboxyl­atometh­oxy)calix[4]arene tris­(carb­oxy­meth­oxy)(carboxyl­atometh­oxy)calix[4]arene–2-(thio­phen-2-yl)-1,3-benzo­thia­zole–dimethyl sulfoxide–water (1/1/2/2), 3Na+·C36H30O122−·C36H31O12−·C11H7NS2·2C2H6OS·2H2O, which provides a new approach into the host–guest chemistry of inclusion complexes. Three packing polymorphs of the same benzo­thia­zole with high Z′ (one with Z′ = 8 and two with Z′ = 4) were also discovered in the course of our desired cocrystallization. The inspection of these polymorphs and a previously known polymorph with Z′ = 2 revealed that Z′ increases as the strength of inter­molecular contacts decreases. Also, these results expand the frontier of invoking calixarenes as a host for non­solvent small mol­ecules, besides providing knowledge on the rare formation of high-Z′ packing polymorphs of simple mol­ecules, such as the target benzo­thiazole.
local.identifier.orcidhttps://orcid.org/0000-0002-3686-7779
local.identifier.orcidhttps://orcid.org/0000-0002-0967-2300
local.identifier.orcidhttps://orcid.org/0000-0001-9913-8971
local.identifier.orcidhttps://orcid.org/0000-0003-2344-5590
local.identifier.orcidhttps://orcid.org/0000-0001-9004-0927
local.publisher.countryBrasil
local.publisher.departmentICX - DEPARTAMENTO DE QUÍMICA
local.publisher.initialsUFMG
local.url.externahttps://journals.iucr.org/paper?S2053229619005886

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