Prognosis of chronic chagas heart disease and other pending clinical challenges

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dc.creatorRosália Morais Torres
dc.creatorCristiano Pisani
dc.creatorMaria da Consolacao Vieira Moreira
dc.creatorDilma do Socorro Moraes de Souza
dc.creatorWilson de Oliveira Junior
dc.creatorSilvia Marinho Martins
dc.creatorJoão Carlos Pinto Dias
dc.creatorDalmo Correia Filho
dc.creatorMaria do Carmo Pereira Nunes
dc.creatorWalderez Dutra
dc.creatorAndre Talvani
dc.creatorAndrea Silvestre Sousa
dc.creatorFernanda de Souza Nogueira
dc.creatorSardinha Mendes
dc.creatorMaurício Ibrahim Scanavacca
dc.date.accessioned2023-12-12T20:10:28Z
dc.date.accessioned2025-09-09T01:01:22Z
dc.date.available2023-12-12T20:10:28Z
dc.date.issued2021
dc.format.mimetypepdf
dc.identifier.doi10.1590/0074-02760210172
dc.identifier.issn00740276
dc.identifier.urihttps://hdl.handle.net/1843/61930
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMemórias do Instituto Oswaldo Cruz
dc.rightsAcesso Aberto
dc.subjectPublic health
dc.subjectPrognosis
dc.subjectChagas Disease
dc.subjectChagas Cardiomyopathy
dc.subject.otherChagas disease
dc.subject.otherPrognosis
dc.subject.otherChagas cardiomyopathy
dc.subject.otherEvolution markers
dc.subject.otherPublic health
dc.titlePrognosis of chronic chagas heart disease and other pending clinical challenges
dc.typeArtigo de periódico
local.citation.epage17
local.citation.issuee210172
local.citation.spage1
local.citation.volume117
local.description.resumoIn this chapter, the main prognostic markers of Chagas heart disease are addressed, with an emphasis on the most recent findings and questions, establishing the basis for a broad discussion of recommendations and new approaches to managing Chagas cardiopathy. The main biological and genetic markers and the contribution of the electrocardiogram, echocardiogram and cardiac magnetic resonance are presented. We also discuss the most recent therapeutic proposals for heart failure, thromboembolism and arrhythmias, as well as current experience in heart transplantation in patients suffering from severe Chagas cardiomyopathy. The clinical and epidemiological challenges introduced by acute Chagas disease due to oral contamination are discussed. In addition, we highlight the importance of ageing and comorbidities in influencing the outcome of chronic Chagas heart disease. Finally, we discuss the importance of public policies, the vital role of funding agencies, universities, the scientific community and health professionals, and the application of new technologies in finding solutions for better management of Chagas heart disease.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0074-02760210172

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