Angiotensin-(1-7) and obesity: role in cardiorespiratory fitness and COVID-19 implications
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Universidade Federal de Minas Gerais
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We have read with interest the recent review by Zbinden-Foncea et al. suggesting that high levels of cardiorespiratory fitness induced by prior exercise training may confer some innate immune protection against coronavirus disease (COVID-19) by attenuating the “cytokine storm syndrome” by modulating angiotensin-converting enzyme 2 (ACE2) effects. However, it is important to highlight that the benefic effects of physical exercise also involves the angiotensin-(1-7)/MAS1 proto-oncogene, GPCR receptor (MAS receptor; Mas) axis activation.
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Obesidade, Angiotensina, COVID-19 (Doença), Exercícios físicos
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https://onlinelibrary.wiley.com/doi/full/10.1002/oby.22949