Cheilitis glandularis: case report and systematic literature review

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dc.creatorSarah Campos Sales
dc.creatorTarcília Aparecida da Silva
dc.creatorSicília Rezende Oliveira
dc.creatorErika Soares Pantuzzo
dc.creatorFernanda Pereira Delgado Costa
dc.creatorMarcus Henrique Xavier
dc.creatorRicardo Alves de Mesquita
dc.creatorLucas Guimarães Abreu
dc.creatorFelipe Eduardo Baires Campos
dc.creatorWagner Henriques de Castro
dc.date.accessioned2025-05-12T23:41:44Z
dc.date.accessioned2025-09-08T22:54:25Z
dc.date.available2025-05-12T23:41:44Z
dc.date.issued2023-02
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1111/ijd.16165
dc.identifier.issn1365-4632
dc.identifier.urihttps://hdl.handle.net/1843/82213
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofInternational Journal of Dermatology
dc.rightsAcesso Restrito
dc.subjectUlcer
dc.subjectLip
dc.subjectInflammation
dc.subjectSalivary glands
dc.subjectCarrier state
dc.subjectSigns and symptoms
dc.subjectPain
dc.subjectEdema
dc.subjectErythema
dc.subjectTherapeutics
dc.titleCheilitis glandularis: case report and systematic literature review
dc.typeArtigo de periódico
local.citation.epage168
local.citation.issue2
local.citation.spage154
local.citation.volume62
local.description.resumoCheilitis glandularis (CG) is a rare inflammatory disease of unknown etiology that affects the minor salivary glands predominantly in the lower lip. In this article, we report the case of an 18-year-old black woman who presented with a deep suppurative type of CG in both lips. In addition, we performed a systematic literature review in five databases (PubMed, Scopus, Web of Science, Ovid, and Embase) to identify CG case reports or case series. A total of 360 references were retrieved in the electronic databases. Thirty-four articles met the inclusion criteria, and six were retrieved through manual search, totaling 40 articles included in the systematic review. Thirty-nine (68.4%) cases occurred in male individuals and 18 (31.6%) in female individuals. The mean age of affected individuals was 40.9 years. Different clinical manifestations ranging from no symptoms to discomfort, pain, swelling, erythema, eversion of the lip, dilated ductal openings, ulcers, and crust have been reported. Among the included CG cases, 41 affected exclusively the lower lip (71.9%). In four cases, the CG only affected the upper lip (7.0%). In 12 cases, the lesion affected both the lower and upper lips (21.1%). Different treatment modalities were adopted in the management of CG. Although the surgical treatment was indicated (42.1%), the conservative treatment with topical medications, as in the present case, resulted in resolution in 21.0% of cases.
local.identifier.orcidhttps://orcid.org/0000-0002-3380-510X
local.identifier.orcidhttps://orcid.org/0000-0001-9623-7835
local.identifier.orcidhttps://orcid.org/0000-0002-8164-2122
local.identifier.orcidhttps://orcid.org/0000-0002-1584-7242
local.identifier.orcidhttps://orcid.org/0000-0002-0697-2463
local.identifier.orcidhttps://orcid.org/0000-0001-5953-4304
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.identifier.orcidhttps://orcid.org/0000-0003-2258-8071
local.identifier.orcidhttps://orcid.org/0000-0001-7781-3737
local.identifier.orcidhttps://orcid.org/0000-0003-2745-2878
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA
local.publisher.initialsUFMG
local.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/ijd.16165

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