Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019

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dc.creatorJonathan M. Kocarnik
dc.creatorRixing Xu
dc.creatorVijayalakshmi S. Bhojaraja
dc.creatorSadia Bibi
dc.creatorAli Bijani
dc.creatorAntonio Biondi
dc.creatorCatherine Bisignano
dc.creatorTone Bjørge
dc.creatorArchie Bleyer
dc.creatorOleg Blyuss
dc.creatorObasanjo Afolabi Bolarinwa
dc.creatorSrinivasa Rao Bolla
dc.creatorEmad Ababneh
dc.creatorDejana Braithwaite
dc.creatorAmanpreet Brar
dc.creatorHermann Brenner
dc.creatorMaria Teresa Bustamante-teixeira
dc.creatorNadeem Shafique Butt
dc.creatorZahid A. Butt
dc.creatorFlorentino Luciano Caetano dos Santos
dc.creatorYin Cao
dc.creatorGiulia Carreras
dc.creatorFerrán Catalá-López
dc.creatorMohsen Abbasi-Kangevari
dc.creatorFrancieli Cembranel
dc.creatorEster Cerin
dc.creatorAchille Cernigliaro
dc.creatorRaja Chandra Chakinala
dc.creatorSoosanna Kumary Chattu
dc.creatorVijay Kumar Chattu
dc.creatorPankaj Chaturvedi
dc.creatorOdgerel Chimed-Ochir
dc.creatorDaniel Youngwhan Cho
dc.creatorDevasahayam J. Christopher
dc.creatorHedayat Abbastabar
dc.creatorDinh-Toi Chu
dc.creatorMichael T. Chung
dc.creatorJoao Conde
dc.creatorSanda Cortés
dc.creatorPaolo Angelo Cortesi
dc.creatorVera Marisa Costa
dc.creatorAmanda Ramos Cunha
dc.creatorOmid Dadras
dc.creatorAmare Belachew Dagnew
dc.creatorSaad M. A. Dahlawi
dc.creatorSherief M. Abd-Elsalam
dc.creatorXiaochen Dai
dc.creatorLalit Dandona
dc.creatorRakhi Dandona
dc.creatorAso Mohammad Darwesh
dc.creatorJosé das Neves
dc.creatorFernando Pio de la Hoz
dc.creatorAsmamaw Bizuneh Demis
dc.creatorEdgar Denova-Gutiérrez
dc.creatorDeepak Dhamnetiya
dc.creatorMandira Lamichhane Dhimal
dc.creatorAmir Abdoli
dc.creatorMeghnath Dhimal
dc.creatorMostafa Dianatinasab
dc.creatorDaniel Diaz
dc.creatorShirin Djalalinia
dc.creatorHuyen Phuc Do
dc.creatorSaeid Doaei
dc.creatorFariba Dorostkar
dc.creatorFrancisco Winter dos Santos Figueiredo
dc.creatorTim Robert Driscoll
dc.creatorHedyeh Ebrahimi
dc.creatorAidin Abedi
dc.creatorSahar Eftekharzadeh
dc.creatorMaha El Tantawi
dc.creatorHassan El-Abid
dc.creatorIffat Elbarazi
dc.creatorHala Rashad Elhabashy
dc.creatorMuhammed Elhadi
dc.creatorShaimaa L. El-jaafary
dc.creatorBabak Eshrati
dc.creatorSharareh Eskandarieh
dc.creatorFirooz Esmaeilzadeh
dc.creatorHassan Abidi
dc.creatorArash Etemadi
dc.creatorSayeh Ezzikouri
dc.creatorMohammed Faisaluddin
dc.creatorEmerito Jose A. Faraon
dc.creatorJawad Fares
dc.creatorFarshad Farzadfar
dc.creatorAbdullah Hamid Feroze
dc.creatorSimone Ferrero
dc.creatorLorenzo Ferro Desideri
dc.creatorIrina Filip
dc.creatorHassan Abolhassani
dc.creatorFlorian Fischer
dc.creatorJames L. Fisher
dc.creatorMasoud Foroutan
dc.creatorTakeshi Fukumoto
dc.creatorPeter Andras Gaal
dc.creatorMohamed M. Gad
dc.creatorMuktar A. Gadanya
dc.creatorSilvano Gallus
dc.creatorMariana Gaspar Fonseca
dc.creatorAbera Getachew Obsa
dc.creatorIsaac Akinkunmi Adedeji
dc.creatorMansour Ghafourifard
dc.creatorAhmad Ghashghaee
dc.creatorNermin Ghith
dc.creatorMaryam Gholamalizadeh
dc.creatorSyed Amir Gilani
dc.creatorThemba G. Ginindza
dc.creatorAbraham Tamirat T. Gizaw
dc.creatorJames C. Glasbey
dc.creatorMahaveer Golechha
dc.creatorPouya Goleij
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dc.creatorQorinah Estiningtyas Sakilah Adnani
dc.creatorRicardo Santiago Gomez
dc.creatorSameer Vali Gopalani
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dc.creatorHouman Goudarzi
dc.creatorGiuseppe Grosso
dc.creatorMohammed Ibrahim Mohialdeen Gubari
dc.creatorMaximiliano Ribeiro Guerra
dc.creatorAvirup Guha
dc.creatorD. Sanjeeva Gunasekera
dc.creatorBhawna Gupta
dc.creatorShailesh M. Advani
dc.creatorVeer Bala Gupta
dc.creatorVivek Kumar Gupta
dc.creatorReyna Alma Gutiérrez
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dc.creatorMohammad Rifat Haider
dc.creatorArvin Haj-Mirzaian
dc.creatorRabih Halwani
dc.creatorRandah R. Hamadeh
dc.creatorSajid Hameed
dc.creatorSamer Hamidi
dc.creatorMuhammad Sohail Afzal
dc.creatorAsif Hanif
dc.creatorShafiul Haque
dc.creatorNetanja L. Harlianto
dc.creatorJosep Maria Haro
dc.creatorAhmed L. Hasaballah
dc.creatorSoheil Hassanipour
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dc.creatorSimon L. Hay
dc.creatorKhezar Hayat
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dc.creatorMohammad Aghaali
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dc.creatorBrenda Yuliana Herrera-serna
dc.creatorClaudiu Herteliu
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dc.creatorRamesh Holla
dc.creatorMd Mahbub Hossain
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dc.creatorMohammad-Salar Hosseini
dc.creatorMostafa Hosseini
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dc.creatorBright Opoku Ahinkorah
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dc.creatorMowafa Househ
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dc.creatorJunjie Huang
dc.creatorFernando N. Hugo
dc.creatorRabia Hussain
dc.creatorNawfal R. Hussein
dc.creatorBing-fang Hwang
dc.creatorIvo Iavicoli
dc.creatorSajjad Ahmad
dc.creatorSegun Emmanuel Ibitoye
dc.creatorFidelia Ida
dc.creatorKevin S. Ikuta
dc.creatorOlayinka Stephen Ilesanmi
dc.creatorIrena M. Ilic
dc.creatorMilena D. Ilic
dc.creatorLalu Muhammad Irham
dc.creatorJessica Y. Islam
dc.creatorRakibul M. Islam
dc.creatorSheikh Mohammed Shariful Islam
dc.creatorTauseef Ahmad
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dc.creatorTamas Joo
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dc.creatorMikk Jürisson
dc.creatorAli Kabir
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dc.creatormd Nuruzzaman Khan
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dc.creatorFrances E. Dean
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dc.creatorYun Jin Kim
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dc.creatorJacek A. Kopec
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dc.creatorParvaiz A. Koul
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dc.creatorWei-chen Lee
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dc.creatorManjula S.
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dc.creatorWoldesellassie M. Mequanint Bezabhe
dc.creatorYihienew Mequanint Bezabih
dc.creatorDevidas S. Bhagat
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dc.creatorKrittika Bhattacharyya
dc.date.accessioned2024-07-22T20:23:56Z
dc.date.accessioned2025-09-09T00:56:32Z
dc.date.available2024-07-22T20:23:56Z
dc.date.issued2022
dc.description.abstractImportância: O Estudo da Carga Global de Doenças, Lesões e Fatores de Risco 2019 (GBD 2019) forneceu estimativas sistemáticas de incidência, morbidade e mortalidade para informar os esforços locais e internacionais para reduzir a carga do câncer. Objetivo: Estimar a carga e as tendências do cancro a nível mundial para 204 países e territórios e por quintis do Índice Sociodemográfico (IDE) de 2010 a 2019. Revisão de evidências: Os métodos de estimativa do GBD 2019 foram usados ​​para descrever a incidência de câncer, mortalidade, anos vividos com incapacidade, anos de vida perdidos e anos de vida ajustados por incapacidade (DALYs) em 2019 e na última década. As estimativas também são fornecidas por quintis do SDI, uma medida composta de nível educacional, renda per capita e taxa de fertilidade total para menores de 25 anos. As estimativas incluem intervalos de incerteza (IU) de 95%. Constatações: Em 2019, houve uma estimativa de 23,6 milhões (II de 95%, 22,2-24,9 milhões) de novos casos de câncer (17,2 milhões excluindo o câncer de pele não melanoma) e 10,0 milhões (II de 95%, 9,36-10,6 milhões) de mortes por câncer em todo o mundo, com uma estimativa de 250 milhões (235-264 milhões) de DALY devido ao cancro. Desde 2010, estes representaram um aumento de 26,3% (IU de 95%, 20,3%-32,3%) em novos casos, um aumento de 20,9% (IU de 95%, 14,2%-27,6%) de mortes e um aumento de 16,0% (IU de 95%, 9,3%-22,8%) nos DALYs. Entre os 22 grupos de doenças e lesões no estudo GBD 2019, o cancro ficou atrás apenas das doenças cardiovasculares em número de mortes, anos de vida perdidos e DALYs a nível mundial em 2019. A carga do cancro diferiu entre os quintis do SDI. A proporção de anos vividos com incapacidade que contribuíram para DALYs aumentou com o ICS, variando de 1,4% (1,1%-1,8%) no quintil de ICS baixo a 5,7% (4,2%-7,1%) no quintil de ICS alto. Embora o quintil de IDE elevado tenha tido o maior número de novos casos em 2019, o quintil de IDE médio teve o maior número de mortes por cancro e de DALYs. De 2010 a 2019, o maior aumento percentual no número de casos e mortes ocorreu nos quintis de ICS baixo e médio-baixo. Conclusões e Relevância: Os resultados desta análise sistemática sugerem que a carga global do cancro é substancial e crescente, com carga diferente por IDE. Estes resultados fornecem estimativas abrangentes e comparáveis ​​que podem potencialmente informar os esforços para o controlo equitativo do cancro em todo o mundo.
dc.format.mimetypepdf
dc.identifier.doi10.1001/jamaoncol.2021.6987
dc.identifier.issn2374-2445
dc.identifier.urihttps://hdl.handle.net/1843/71191
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJAMA Oncology
dc.rightsAcesso Aberto
dc.subjectNeoplasias
dc.subjectNeoplasias de cabeça e pescoço
dc.subjectCarga global da doença
dc.titleCancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019
dc.typeArtigo de periódico
local.citation.epage444
local.citation.issue3
local.citation.spage420
local.citation.volume8
local.description.resumoImportance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. Evidence Review: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). Findings: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. Conclusions and Relevance: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://jamanetwork.com/journals/jamaoncology/fullarticle/2787350

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