Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE) - Brazil

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dc.creatorBárbara Zille de Queiroz
dc.creatorNayza Maciel de Britto Rosa
dc.creatorDaniele Sirineu Pereira
dc.creatorRenata Antunes Lopes
dc.creatorAmanda Aparecida Oliveira Leopoldino
dc.creatorRonaldo Luiz Thomasini
dc.creatorDiogo Carvalho Felício
dc.creatorLygia Paccini Lustosa
dc.creatorLeani Souza Máximo Pereira
dc.date.accessioned2022-07-13T13:23:44Z
dc.date.accessioned2025-09-08T22:49:33Z
dc.date.available2022-07-13T13:23:44Z
dc.date.issued2020-03
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.identifier.doihttps://doi.org/10.1007/s00586-019-06168-x
dc.identifier.issn1432-0932
dc.identifier.urihttps://hdl.handle.net/1843/43229
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofEuropean Spine Journal
dc.rightsAcesso Restrito
dc.subjectEnvelhecimento
dc.subjectBack Complaints in the Elders (BACE)
dc.subjectCitocinas
dc.subjectDor lombar
dc.subject.otherAging
dc.subject.otherBACE
dc.subject.otherCytokines
dc.subject.otherDisability
dc.subject.otherFall risk
dc.subject.otherLow back pain
dc.titleInflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE) - Brazil
dc.typeArtigo de periódico
local.citation.epage555
local.citation.issue3
local.citation.spage549
local.citation.volume29
local.description.resumoPurpose: To investigate the association between plasma levels of inflammatory cytokines (interleukin [IL]-1-β, IL-6, tumor necrosis factor [TNF]-α, and the soluble TNF receptor 1 [sTNF-R1]), disability, and risk of falls in older women with acute low back pain (LBP). Methods: This cross-sectional study comprised a subsample of older women from the Back Complaints in the Elders international cohort study. Plasma levels of IL-1-β, IL-6, TNF-α, and sTNF-R1 were measured using enzyme-linked immunosorbent assays. Pain was assessed using the Numerical Pain Scale and McGill Pain Questionnaire, while disability was measured using the Roland Morris Questionnaire and gait speed. Risk of falls was estimated using the Physiological Profile Assessment. Linear regression model was used to verify the association between independent variables and fall risk. Results: One hundred and ten women (aged 69.97 ± 5.5 years) with acute LBP were included. The regression model showed an association between the risk of falls and IL-6 levels, pain, gait speed, and years of education. It also explained 21.2% of risk of falls variance. The model equation was: fall risk = 1.28 + (0.19 IL-6) + (0.02 quality of pain) + (− 0.71 gait speed) + (−0 .17 educational level). Conclusions: This study showed an association between risk of falls and IL-6, pain, gait speed, and educational level in older women with LBP.
local.identifier.orcidhttps://orcid.org/ 0000-0003-1014-1512
local.identifier.orcidhttps://orcid.org/0000-0002-4868-9244
local.identifier.orcidhttps://orcid.org/0000-0002-0919-1320
local.identifier.orcidhttps://orcid.org/ 0000-0001-7253-4392
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s00586-019-06168-x

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