Malocclusion in individuals with osteogenesis imperfecta: a systematic review and meta-analysis
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Universidade Federal de Minas Gerais
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Artigo de periódico
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Membros da banca
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Objective: To evaluate whether individuals with osteogenesis imperfecta (OI) aremore affected by malocclusion than individuals without OI. Materials and Methods: Searches in PubMed, Ovid, Web of Science, Scopus, Lilacsand gray literature were performed. Data extraction was conducted by two research-ers. Risk of bias assessment employing the Newcastle-Ottawa Scale and meta-anal-ysis were conducted. Results were provided with mean difference (MD), odds ratio(OR) and 95% confidence interval (CI). Strength of evidence was determined.Results: Six cross-sectional studies were included. In comparison with individualswithout OI, the group with OI had 19.69-fold greater chance of exhibiting AngleClass III malocclusion (OR = 19.69, CI: 9.00–43.09) and presenting anterior crossbitegreater (MD = 6.08, CI: 2.40–9.77). Individuals without OI had a significantly greaterANB angle (MD = 3.88, CI: 1.15–6.61) and SNA angle (MD = 2.11, CI: 0.24–3.98) incomparison with those with OI. No difference between groups was found for SNB(MD = −0.50, CI: −2.21 to 1.21) and open bite (MD = 0.98, CI: −0.29 to 2.25). Moststudies included had moderate methodological quality. Strength of evidence was lowor very low. Conclusions: The occurrence of Angle Class III malocclusion and anterior crossbitewas greater among individuals with OI compared to those without OI. These findingscan assist stakeholders about the occlusal abnormalities affecting OI individuals.
Abstract
Assunto
Malocclusion, Oral health, Osteogenesis imperfecta, Rare diseases
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Malocclusion, Oral health, Osteogenesis imperfecta, Rare diseases
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https://onlinelibrary.wiley.com/doi/10.1111/odi.13715