Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits

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dc.creatorEduardo Louzada da Costa
dc.creatorLuiz Eduardo Moreira Teixeira
dc.creatorBruno Jannotti Pádua
dc.creatorIvana Duval Araújo
dc.creatorLeonardo de Souza Vasconcellos
dc.creatorLuide Scalioni Borges Dias
dc.date.accessioned2023-05-18T20:15:44Z
dc.date.accessioned2025-09-09T01:13:47Z
dc.date.available2023-05-18T20:15:44Z
dc.date.issued2017
dc.format.mimetypepdf
dc.identifier.doi10.1590/s0102-865020170100000004
dc.identifier.issn01028650
dc.identifier.urihttps://hdl.handle.net/1843/53603
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofActa Cirúrgica Brasileira
dc.rightsAcesso Aberto
dc.subjectLigamento Colateral Médio do Joelho
dc.subjectTraumatismos do Joelho
dc.subjectJoelho
dc.subjectRatos
dc.subject.otherMedial Collateral Ligament
dc.subject.otherKnee
dc.subject.otherKnee Injuries
dc.subject.otherRabbits
dc.titleBiomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits
dc.typeArtigo de periódico
local.citation.epage835
local.citation.issue10
local.citation.spage827
local.citation.volume32
local.description.resumoPurpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups. Results: Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p =0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001).Conclusion: The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament.
local.identifier.orcidhttps://orcid.org/0000-0002-2034-0294
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTOR
local.publisher.departmentMED - DEPARTAMENTO DE CIRURGIA
local.publisher.departmentMED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR
local.publisher.initialsUFMG
local.url.externahttps://www.scielo.br/j/acb/a/QTZ9zhn8pDs9dgS9NJsjcYj/?lang=en

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