Determinação de intervalos de referência para o hemograma em idosos da região metropolitana de Belo Horizonte

Abstract

Objectives: to establish reference values (RV) of 15 blood count parameters for elderly and compare the results among other papers in literature. Method: in this transversal study, data on elderly people attended by the Programa Mais Vida (PMV) of the Clinical Hospital of Universidade Federal de Minas Gerais (HC-UFMG) were evaluated based on the Functional Clinical Vulnerability Index (IVCF-20) and individual Care Plan (PC). Blood samples were processed on the same day at the HC-UFMG using the Sysmex ™ XN-3000 analytical system. A reference population was defined after exclusion and inclusion criteria’s. The measurements of 15 blood count parameters (red blood cells, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelets, MPV, global leukocytes, neutrophils, lymphocytes, monocytes, eosinophils and basophils) were assessed by QQ plots, boxplots and Anderson-Darling normality test. Outliers were identified by Dixon test and D/R ratio. Descriptive statistics for each parameter were defined (mean, median, truncated mean, quartiles, maximum and minimum values, amplitude, standard deviation, asymmetry and kurtosis) and the partition for age subgroups after 60 years old and for gender was studied through Harris-Boyd test, according to CLSI C28-A3c guidelines. Results: RV were established in 686 selected elderly people, using the 2.5% and 97.5% percentiles and 90% CI. In contrast to age, it was necessary to stratify the RRs established for red blood cells, hemoglobin, hematocrit and platelets. Hemoglobin levels reduce in male after age 80. In women, platelets and lymphocytes were higher. Conclusions: reference values of 15 blood count parameters for elderly were established at HC-UFMG. The RV were similar to other papers in literature and could help to adequate read blood count results and clinical follow-up in elderly people.