Subclinical thyroid dysfunction was not associated with cardiac arrhythmias in a cross-sectional analysis of the elsa-brasil study

Página do item simplificado
dc.creatorKamilla Maria Araújo Brandãorajão
dc.creatorAntonio Luiz Pinho Ribeiro
dc.creatorValéria Maria Azeredo Passos
dc.creatorIsabela Judith Martins Benseñor
dc.creatorPedro Guatimosim Vidigal
dc.creatorCleber Pinto Camacho
dc.creatorMaria de Fátima Haueisen Sander Diniz
dc.date.accessioned2024-01-19T18:28:53Z
dc.date.accessioned2025-09-09T00:46:36Z
dc.date.available2024-01-19T18:28:53Z
dc.date.issued2019
dc.format.mimetypepdf
dc.identifier.doi10.5935/abc.20190037
dc.identifier.issn0066782X
dc.identifier.urihttps://hdl.handle.net/1843/63154
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofArquivos Brasileiros de Cardiologia
dc.rightsAcesso Aberto
dc.subjectThyroid Diseases
dc.subjectPathologic Processes
dc.subjectThyrotrophs
dc.subjectArrhythmias, Cardiac
dc.subjectAdult
dc.subject.otherThyroid Diseases
dc.subject.otherPathologic Processes
dc.subject.otherThyrotrophs
dc.subject.otherArrhythmias, Cardiac
dc.subject.otherAdult
dc.titleSubclinical thyroid dysfunction was not associated with cardiac arrhythmias in a cross-sectional analysis of the elsa-brasil study
dc.typeArtigo de periódico
local.citation.epage766
local.citation.issue6
local.citation.spage758
local.citation.volume112
local.description.resumoObjective: To investigate whether STD was associated with cardiac arrhythmias in a cohort of middle-aged and older adults.Methods: Baseline data of the Longitudinal Study of Adult Health, ELSA–Brasil (35–74 years) were collected from 2008 to 2010. After exclusion of clinical hypothyroidism and hyperthyroidism, participants were categorized as euthyroidism (TSH = 0.4–4.0 µU/mL), subclinical hypothyroidism (TSH > 4.0 µU/mL; FT4 = 0.8–1.9 ng/dL), and subclinical hyperthyroidism (TSH < 0.4 µU/mL; FT4 = 0.8–1.9 ng/dL). The prevalence rates of tachycardia (HR > 100) and bradycardia (HR < 60), atrial fibrillation/flutter, conduction disorders, extrasystoles, low QRS voltage, prolonged QT intervals, and persistent supraventricular rhythms were compared between groups after adjusting for age, sex, comorbidities, lifestyle, body mass index and medications.Results: The HR data of 13,341 participants (52% female; median age, 51 years) and the electrocardiogram readings of 11,795 were analyzed; 698 participants (5.23%) were classified as subclinical hypothyroidism, 193 (1.45%) as subclinical hyperthyroidism, and 12,450 (93.32%) as euthyroidism. The prevalence of rhythm and conduction disorders was similar, as were HR medians, even in the subgroups with TSH < 0.01 UI/mL or > 10.0 UI/mL or in older adults. Conduction disorders were less prevalent in older adults with subclinical hypothyroidism (adjusted OR = 0.44; 95% CI 0.24 to 0.80).Conclusion: In this large, multicenter and cross-sectional study, STD was not associated with cardiac arrhythmias, but a longitudinal assessment is necessary.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.departmentMED - DEPARTAMENTO DE PROPEDÊUTICA COMPLEMENTAR
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.5935/abc.20190037

Arquivos

Pacote original

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
Subclinical Thyroid Dysfunction was not Associated with Cardiac pdfa.pdf
Tamanho:
294.54 KB
Formato:
Adobe Portable Document Format
Baixar

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG