Control of Haemonchus contortus in sheep using basidiocarps of Agaricus blazei Murril

dc.creatorThallyta Maria Vieira
dc.creatorLeydiana Duarte Fonseca
dc.creatorGabriela Almeida Bastos
dc.creatorViviane de Oliveira Vasconcelos
dc.creatorMaria Luiza França Silva
dc.creatorFranciellen Morais Costa
dc.creatorAdriano Vinicius de Paiva Ferreira
dc.creatorNeide Judith Faria de Oliveira
dc.creatorEduardo Robson Duarte
dc.date.accessioned2022-12-08T15:17:48Z
dc.date.accessioned2025-09-08T23:44:23Z
dc.date.available2022-12-08T15:17:48Z
dc.date.issued2017-01-31
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.description.sponsorshipOutra Agência
dc.identifier.doi10.1007/s11259-017-9677-x
dc.identifier.issn1573-7446
dc.identifier.urihttps://hdl.handle.net/1843/47845
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofVeterinary Research Communications
dc.rightsAcesso Aberto
dc.subjectHaemonchus contortus
dc.subjectBasidiomicetos
dc.subjectOvinos - Doenças
dc.titleControl of Haemonchus contortus in sheep using basidiocarps of Agaricus blazei Murril
dc.typeArtigo de periódico
local.citation.epage106
local.citation.spage99
local.citation.volume41
local.description.resumoObjective: this study evaluated the effects in vitro and in vivo of Agaricus blazei against Haemonchus contortus in sheep. Methods: the in vitro efficacy of aqueous extract on egg hatching inhibition (EHI) was investigated and after 72 h incubation with varying concentrations the effects on, blastomeres, embryonated eggs, and first stage larvae (L1) were evaluated. Larval development inhibition (LDI) for dry powder and the aqueous extract were evaluated in fecal cultures of sheep infected with H. contortus. In vivo efficacy was determined by reduction in fecal egg count (FEC). Lambs were treated with powder A. blazei (11.4 g/kg pc) or trichlorfon, or were untreated and the possible toxicity of this fungus was monitored by plasmatic enzyme analysis. Results: concentrations equal to and higher than 3.62 mg/mL and of aqueous extract were 100% effective in the EHI test. In the LDI test, LC90 was estimated for 5.66 and 106.0 mg/g fecal culture for aqueous extract and powder, respectively. The mean FEC in lambs 14 days post-treatment with A. blazei powder was significantly lower than observed for the negative control, and the serum levels of aspartate transaminase and alanine transaminase were normal. Conclusion: the fungi supplementation promotes, respectively, high and moderate anthelmintic efficacy with in vitro and in vivo tests, respectively, suggesting it as an alternative or complementary treatment for haemonchosis in sheep.
local.publisher.countryBrasil
local.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s11259-017-9677-x

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