Quality of life after diagnosis of neurally mediated reflex syncope by tilt test
| dc.creator | Cláudia Madeira Miranda | |
| dc.creator | Rose Mary Ferreira Lisboa da Silva | |
| dc.creator | Edson Dell"amore Filho | |
| dc.creator | Izabela Maria Azeredo Nascimento | |
| dc.date.accessioned | 2025-07-31T18:01:50Z | |
| dc.date.accessioned | 2025-09-09T00:23:44Z | |
| dc.date.available | 2025-07-31T18:01:50Z | |
| dc.date.issued | 2024 | |
| dc.format.mimetype | ||
| dc.identifier.doi | 10.36660/ijcs.20230017 | |
| dc.identifier.issn | 23594802 | |
| dc.identifier.uri | https://hdl.handle.net/1843/83949 | |
| dc.language | eng | |
| dc.publisher | Universidade Federal de Minas Gerais | |
| dc.rights | Acesso Aberto | |
| dc.subject | Syncope | |
| dc.subject | Quality of Life | |
| dc.subject | Physical Examination | |
| dc.subject.other | Syncope | |
| dc.subject.other | Quality of Life | |
| dc.subject.other | Physical Examination | |
| dc.title | Quality of life after diagnosis of neurally mediated reflex syncope by tilt test | |
| dc.type | Artigo de periódico | |
| local.citation.epage | 9 | |
| local.citation.issue | e20230017 | |
| local.citation.spage | 1 | |
| local.citation.volume | 37 | |
| local.description.resumo | Background: Vasovagal syncope (VVS) results in impaired quality of life (QoL). The response during the head-up tilt test (HUTT) influences QoL and recurrence. Objectives: To analyze the influence of the type of HUTT response on QoL in patients with VVS and recurrence of events after the exam. Methods: The SF-36 and Impact of Syncope on Quality of Life (ISQL) questionnaires were applied over 12 months after the HUTT. Unpaired Student’s t test was used for differences between 2 groups of quantitative data with normal distribution. The recurrence of syncope episodes was analyzed using a Kaplan-Meier curve, and the log-rank test was applied to compare the curves regarding responses to the HUTT. Statistical significance was set at p value < 0.05. Results: We analyzed 82 patients (43.7 years old), 69% with previous recurrence (2.8 prior episodes). Cardioinhibitory response occurred in 46 patients; vasodepressor response occurred in 36, and 85.4% of patients received nonpharmacological treatment after the HUTT. During clinical follow-up, 43.9% had recurrence, mainly young patients (35.7 years; p = 0.002). On the SF-36, the best score was in functional capacity in men (p = 0.04) and patients without prior trauma (p = 0.001). There were lower limitations due to pain in patients without prior trauma (p = 0.003) and patients without prodromes (p = 0.009). On the ISQL, there were better mean scores in men (p = 0.002) and in patients without prior trauma (p = 0.02). Patients with cardioinhibitory response had better SF-36 and ISQL scores (p < 0.001). There was greater VVS recurrence in the cardioinhibitory response group (log-rank p = 0.011; hazard ratio: 8.48; 95% confidence interval: 7.59 to 9.3) from the second to the fourth month, with stabilization in the eighth month after the HUTT, when compared to patients with vasodepressor response. Conclusions: The majority of patients with VVS reproduced during the HUTT under non-pharmacological termical did not report worsening of QoL during clinical follow-up. Worse QoL was observed in non-young patients and in patients with vasodepressor response, and it was not influenced by recurrence after the HUTT. | |
| local.publisher.country | Brasil | |
| local.publisher.department | MED - DEPARTAMENTO DE CLÍNICA MÉDICA | |
| local.publisher.initials | UFMG | |
| local.url.externa | https://doi.org/10.36660/ijcs.20230017 |