Scintigraphic imaging of Staphylococcus aureus infection using 99mTc radiolabeled aptamers

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dc.creatorSara Roberta dos Santos
dc.creatorCamila Maria de Sousa Lacerda
dc.creatorIêda Mendes Ferreira
dc.creatorAndré Luís Branco de Barros
dc.creatorSimone Odília Fernandes
dc.creatorValbert Nascimento Cardoso
dc.creatorAntero Silva Ribeiro de Andrade
dc.date.accessioned2022-05-09T19:39:45Z
dc.date.accessioned2025-09-08T23:20:57Z
dc.date.available2022-05-09T19:39:45Z
dc.date.issued2017-10
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.identifier.doi10.1016/j.apradiso.2017.06.043
dc.identifier.issn0969-8043
dc.identifier.urihttps://hdl.handle.net/1843/41485
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofApplied Radiation and Isotopes
dc.rightsAcesso Restrito
dc.subjectRadiomarcados
dc.subjectStaphylococcus aureus
dc.subjectCintilografia
dc.subject.otherDiagnosis
dc.subject.otherBacterial infection
dc.subject.otherRadiopharmaceutical
dc.subject.otherTechnetium-99m
dc.subject.otherAptamer
dc.titleScintigraphic imaging of Staphylococcus aureus infection using 99mTc radiolabeled aptamers
dc.typeArtigo de periódico
local.citation.epage27
local.citation.spage22
local.citation.volume128
local.description.resumoStaphylococcus aureus is a specie of great medical importance associated with many infections as bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device related infections. Early identification of infectious foci is crucial for successful treatment. Scintigraphy could contribute to this purpose since specific radiotracers were available. Aptamers due to their high specificity have great potential for radiopharmaceuticals development. In the present study scintigraphic images of S. aureus infectious foci were obtained using specific S. aureus aptamers radiolabeled with 99mTc.
local.publisher.countryBrasil
local.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOS
local.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S0969804317304384

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