Profile of the leprosy endemic in the disctrict of murrupula, nampula, mozambique: a population-based study

dc.creatorGabriela Cassiaribeiro
dc.creatorDaniele s Lages
dc.creatorAna Thereza Chaves Lages
dc.creatorVânia b Souza
dc.creatorAbdoulaye Marega
dc.creatorFrancisco Carlos Félix Lana
dc.creatorManoel Otávio da Costa Rocha
dc.date.accessioned2024-01-11T19:20:11Z
dc.date.accessioned2025-09-08T23:42:18Z
dc.date.available2024-01-11T19:20:11Z
dc.date.issued2022
dc.format.mimetypepdf
dc.identifier.doi10.1590/0037-8682-0321-2022
dc.identifier.issn00378682
dc.identifier.urihttps://hdl.handle.net/1843/62643
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical
dc.rightsAcesso Aberto
dc.subjectLeprosy
dc.subjectEpidemiology
dc.subjectPublic health
dc.subject.otherLeprosy
dc.subject.otherEpidemiology
dc.subject.otherPublic health
dc.titleProfile of the leprosy endemic in the disctrict of murrupula, nampula, mozambique: a population-based study
dc.typeArtigo de periódico
local.citation.epage9
local.citation.issuee0321-2022
local.citation.spage1
local.citation.volume56
local.description.resumoBackground: Leprosy is a neglected chronic infection caused by Mycobacterium leprae, that is curable. The magnitude of the disease and severity of the debilitation it causes renders leprosy a public health problem. This study aimed to analyze the endemic profile of leprosy in the Murrupula district and evaluate the socioeconomic, clinical, and serological profiles of leprosy contacts. Methods: A cross-sectional study of patients with leprosy diagnosed between 2013 and 2017 and their household and community contacts was conducted in Murrupula District, Nampula Province, Mozambique. Interviews, simplified dermatoneurological examinations, Mycobacterium leprae flow (ML Flow) tests, and Mitsuda tests were performed. Results: Most of the leprosy cases were multibacillary. The patients had some degree of physical disability. ML Flow positivity was more common in household contacts of the patients diagnosed with leprosy and in community individuals who spontaneously presented for testing. In total, 17 patients were diagnosed with leprosy. Conclusions: This study revealed an active chain of transmission, hidden prevalence, and operational deficiencies in leprosy surveillance and care. The results suggest that the implementation of a public health policy for leprosy prevention and control in Nampula Province is necessary. In future, the possibility of expanding the policy to the entire country should be considered
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://doi.org/10.1590/0037-8682-0741-2021

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