Avaliação de risco para nefropatia induzida por contraste iodado após exame de imagem em hospital terciário

Abstract

This dissertation consists of an article, addresses the nephropathy induced by contrast media parenteral (NICI) since its incidence, importance of diagnosis and prognosis, in addition to the main determinants of their occurrence. The sample involved 416 patients at a tertiary hospital and who underwent angiography with contrast media in the period August 22, 2008 to March 30, 2009. The socio-demographic, clinical, medication use and the type and volume of contrast used, were recorded for each patient. Serum creatinine was measured before and 48hours to 72 hours after the procedure. The NICI was defined as the relative increase in creatinine of 25% or absolute increase of 0.5 mg / dL at baseline, after 48-72 hours of contrast administration in the absence of other causes of acute renal failure. The NICI occurred in 68 patients (16.9%). A large number of variables were present but, after multivariate analysis, a higher incidence of NICI occurred with the mode of action of diagnostic arteriography alone (p = 0.031) and diuretic use prior to the procedure (p = 0.044). A high incidence of NICI was observed in our sample of patients in tertiary hospital, composed of elderly patients with high prevalence of risk factors for nephropathy. As this type of population is generally one that may be used to complete these procedures, protocols or measures for risk identification, prevention and treatment for NICI should be made available.