Childhood family adversity and recurrent depression in adulthood: the findings of three ELSA-Brasil follow-up visits

dc.creatorMaíra Barroso Léo
dc.creatorSandhi Maria Barreto
dc.creatorRosane Harter Griep
dc.creatorAna Luísa Patrão
dc.creatorLidyane do Valle Camelo
dc.creatorMaria Carmen Viana
dc.creatorLuana Giatti
dc.date.accessioned2026-01-12T20:55:28Z
dc.date.issued2024-12
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e Projetos
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doihttps://doi.org/10.47626/1516-4446-2024-3914
dc.identifier.issn1809-452X
dc.identifier.urihttps://hdl.handle.net/1843/1366
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofBrazilian Journal of Psychiatry
dc.rightsAcesso aberto
dc.rightsCC0 1.0 Universalen
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.subjectEpidemiologia
dc.subjectDepressão
dc.subjectSaúde mental
dc.subjectRelações familiares
dc.subject.otherAdverse childhood experiences
dc.subject.otherChildhood trauma
dc.subject.otherDepression
dc.subject.otherCohort study
dc.titleChildhood family adversity and recurrent depression in adulthood: the findings of three ELSA-Brasil follow-up visits
dc.typeArtigo de periódico
local.citation.epage8
local.citation.spage1
local.citation.volume47
local.description.resumoObjective: This study investigated the association between childhood family adversity and depression in a cohort of Brazilian adults over three visits. Methods: A total of 12,636 participants from the Longitudinal Study of Adult Health (ELSA-Brasil), baseline (2008-2010) and followed up in 2012-2014 and 2017-2019, were included. Five types of family dysfunction and the childhood family dysfunction score (0, 1, and X 2 dysfunctions) were used. The Clinical Interview Schedule-Revised was used to assess depression in visits 1 and 2 or 3. Multinomial logistic regression models estimated crude and adjusted OR and 95%CI. Results: The mean age of the sample was 59.6 (SD, 8.8) years, 7.4% presented depression in one visit, and 2.2% presented it in two or three visits. After adjustment, compared to no family dysfunction, mental disorder (OR = 3.91; 95%%CI 2.94-5.21), substance abuse (OR = 2.14; 95%CI 1.65-2.77), and parental separation/divorce (OR = 1.55; 95%CI 1.12-2.15) increased the odds of depression in two or three visits. Exposure to X 2 types of family dysfunction increased the odds of depression in one, and two or three visits in a dose-response gradient. Conclusion: Exposure to childhood family dysfunction contributes to the occurrence and recurrence of depression in adults. Interventions to prevent dysfunctional family environments and their repercussions on children can reduce the burden of depression.
local.identifier.orcidhttps://orcid.org/0000-0002-4074-2856
local.identifier.orcidhttps://orcid.org/0000-0001-7383-7811
local.identifier.orcidhttps://orcid.org/0000-0002-6250-2036
local.identifier.orcidhttps://orcid.org/0000-0002-2027-5461
local.identifier.orcidhttps://orcid.org/0000-0001-7471-7547
local.identifier.orcidhttps://orcid.org/0000-0002-0464-4845
local.identifier.orcidhttps://orcid.org/0000-0001-5454-2460
local.publisher.countryBrasil
local.publisher.departmentMEDICINA - FACULDADE DE MEDICINA
local.publisher.initialsUFMG
local.subject.cnpqCIENCIAS DA SAUDE::MEDICINA::PSIQUIATRIA
local.url.externahttps://www.bjp.org.br/how-to-cite/3580/en-US

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