Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/40712
Tipo: Artigo de Periódico
Título: Data on statistical experimental design to formulate amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid for the treatment of vulvovaginal candidiasis
Autor(es): Carolina Mirtes Melo
Jéssica Ferreira Cardoso
Fernanda Barçante Perasoli
Maria Betânia de Freitas Marques
Wagner da Nova Mussel
Sandra Aparecida de Lima Moura
Gisele Rodrigues da Silva
Resumo: Data described in this article are related to the research article entitled “Amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid (AMP EUD nanoparticles/HA) for the treatment of vulvovaginal candidiasis”. In this work, we report original data on the statistical experimental design to formulate uncoated AMP EUD nanoparticles, data on the validation of spectrophotometric method to quantify the AMP released from uncoated EUD nanoparticles and coated with HA to obtain the in vitro drug release profiles as well as the drug encapsulation efficiency. In addition, we describe original data on characterization, including diameter size, polydispersity index, zeta potential, FTIR, DSC/TG, and XRD; data on diameter of in vitro inhibition halos of Candida albicans; and on the vaginal burden of infected animals treated with uncoated AMP EUD nanoparticles and AMP EUD nanoparticles/HA. Finally, different histological sections of endocervix collected from treated and untreated animals were inserted into this manuscript.
Assunto: Candidíase vulvovaginal
Idioma: eng
País: Brasil
Editor: Universidade Federal de Minas Gerais
Sigla da Instituição: UFMG
Departamento: FAR - DEPARTAMENTO DE ALIMENTOS
ICX - DEPARTAMENTO DE QUÍMICA
Tipo de Acesso: Acesso Aberto
Identificador DOI: 10.1016/j.dib.2020.105311
URI: http://hdl.handle.net/1843/40712
Data do documento: Abr-2020
metadata.dc.url.externa: https://www.sciencedirect.com/science/article/pii/S2352340920302055?via%3Dihub
metadata.dc.relation.ispartof: Data in Brief
Aparece nas coleções:Artigo de Periódico



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