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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/40712
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dc.creatorCarolina Mirtes Melopt_BR
dc.creatorJéssica Ferreira Cardosopt_BR
dc.creatorFernanda Barçante Perasolipt_BR
dc.creatorMaria Betânia de Freitas Marquespt_BR
dc.creatorWagner da Nova Musselpt_BR
dc.creatorSandra Aparecida de Lima Mourapt_BR
dc.creatorGisele Rodrigues da Silvapt_BR
dc.date.accessioned2022-04-01T22:08:11Z-
dc.date.available2022-04-01T22:08:11Z-
dc.date.issued2020-04-
dc.citation.volume29pt_BR
dc.citation.spage1pt_BR
dc.citation.epage22pt_BR
dc.identifier.doi10.1016/j.dib.2020.105311pt_BR
dc.identifier.issn2352-3409pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/40712-
dc.description.resumoData described in this article are related to the research article entitled “Amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid (AMP EUD nanoparticles/HA) for the treatment of vulvovaginal candidiasis”. In this work, we report original data on the statistical experimental design to formulate uncoated AMP EUD nanoparticles, data on the validation of spectrophotometric method to quantify the AMP released from uncoated EUD nanoparticles and coated with HA to obtain the in vitro drug release profiles as well as the drug encapsulation efficiency. In addition, we describe original data on characterization, including diameter size, polydispersity index, zeta potential, FTIR, DSC/TG, and XRD; data on diameter of in vitro inhibition halos of Candida albicans; and on the vaginal burden of infected animals treated with uncoated AMP EUD nanoparticles and AMP EUD nanoparticles/HA. Finally, different histological sections of endocervix collected from treated and untreated animals were inserted into this manuscript.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOSpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofData in Briefpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectHyaluronic acidpt_BR
dc.subjectAmphotericin Bpt_BR
dc.subjectAmphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acidpt_BR
dc.subjectEudragit RL100pt_BR
dc.subjectVulvovaginal candidiasispt_BR
dc.subject.otherCandidíase vulvovaginalpt_BR
dc.titleData on statistical experimental design to formulate amphotericin B-loaded Eudragit RL100 nanoparticles coated with hyaluronic acid for the treatment of vulvovaginal candidiasispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2352340920302055?via%3Dihubpt_BR
Appears in Collections:Artigo de Periódico

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