1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/40865
Full metadata record
DC FieldValueLanguage
dc.creatorStephanie de Souza Theodoropt_BR
dc.creatorThaila Cristina Putarovpt_BR
dc.creatorCaroline Tiemipt_BR
dc.creatorLara Mantovani Volpept_BR
dc.creatorCarlos Alberto Ferreira de Oliveirapt_BR
dc.creatorMaria Beatriz de Abreu Glóriapt_BR
dc.creatorAulus Cavalieri Carciofipt_BR
dc.date.accessioned2022-04-06T23:49:06Z-
dc.date.available2022-04-06T23:49:06Z-
dc.date.issued2019-11-
dc.citation.volume14pt_BR
dc.citation.issue11pt_BR
dc.identifier.doi10.1371/journal.pone.0225659pt_BR
dc.identifier.issn1932-6203pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/40865-
dc.description.resumoDerivatives of yeast cell wall (YCW) have been studied for their potential prebiotic effects. Recently, new purified and solublepreparations have been developed in an attempt to increase their biological actions. Two YCW preparations, one conventional andanother with higher solubility of the mannan oligosaccharide fraction, were evaluated on dogs. One food formulation was used,divided into the following treatments: CON–control, without yeast cell wall addition; YCW–addition of 0.3% of a conventional yeascell wall extract; YCWs–addition of 0.3% of a yeast cell wall extract with high mannan oligosaccharide solubility. Twenty-four beagledogs were used, eight per food, distributed on a block design. Blocks lasted 32 days, and TNF-a, IL-6, IL-10, ex vivo production ofhydrogen peroxide and nitric oxide by peripheral neutrophils and monocytes, phagocytic index, and fecal IgA were evaluated at thebeginning and end of each period. Additionally, nutrient digestibility, feces production and quality, and fermentation products werequantified. The results were evaluated by analysis of variance and compared using the Tukey test (P<0.05), using the basalimmunological parameters as a covariate. The inclusion of YCWs reduced fat digestibility (P<0.05), increased the concentration ofbutyrate and putrescine, and reduced lactate in feces (P<0.05), showing that mannan oligosaccharide solubilization resulted inhigher fermentation of this compound and altered the metabolism of the gut microbiota. Lower IL-6 on serum was verified for dogsfed the YCWs diet (P<0.05), suggesting a reduction in the inflammatory activity of dogs. Higher phagocytic index was verified forperipheral monocytes after the intake of the YCW food, suggesting better innate immunity. In conclusion, the solubilization of themannooligosaccharide fraction alters its interaction with gut microbiota and biological actions in animals, although both yeast cellwall preparations exhibited prebiotic effects on dogs.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOSpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE PRODUTOS FARMACÊUTICOSpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPlos onept_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCell wall preparationspt_BR
dc.subjectPotential prebioticpt_BR
dc.subjectDogspt_BR
dc.subject.otherCiência e Tecnologia de Alimentospt_BR
dc.subject.otherMedicina Veterináriapt_BR
dc.subject.otherCachorrospt_BR
dc.titleEffects of the solubility of yeast cell wall preparations on their potential prebiotic properties in dogspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225659pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Effects of the solubility of yeast cell wall preparations on their potential prebiotic properties in dogs.pdf826.68 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.