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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/41938
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dc.creatorWilliam Gustavo Limapt_BR
dc.creatorJúlio César Moreira Britopt_BR
dc.creatorBárbara Gatti Cardosopt_BR
dc.creatorValbert Nascimento Cardosopt_BR
dc.creatorMagna Cristina de Paivapt_BR
dc.creatorMaria Elena de Limapt_BR
dc.creatorSimone Odília Antunes Fernandespt_BR
dc.date.accessioned2022-05-24T21:50:42Z-
dc.date.available2022-05-24T21:50:42Z-
dc.date.issued2020-
dc.citation.volume39pt_BR
dc.citation.issue8pt_BR
dc.citation.spage1427pt_BR
dc.citation.epage1438pt_BR
dc.identifier.doi10.1007/s10096-020-03876-xpt_BR
dc.identifier.issn0934-9723pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/41938-
dc.description.resumoWe conducted a systematic review and meta-analysis to determine the rate of polymyxin resistance among Acinetobacter baumannii isolates causing infection in hospitalized patients around the world during the period of 2010-2019. The systematic review was performed on September 1, 2019, using PubMed/MEDLINE, Scopus, and Web of Science; studies published after January 1, 2010, were selected. The data were summarized in tables, critically analyzed, and treated statistically using the RStudio® Software with Meta package and Metaprop Command. After applying exclusion factors, 41 relevant studies were selected from 969 articles identified on literature search. The overall rate of polymyxin-resistant A. baumannii (PRAB) related to hospitalized patients was estimated to be 13% (95% CI, 0.06-0.27), where a higher rate was observed in America (29%; 95% CI, 0.12-0.55), followed by Europe (13%; 95% CI, 0.02-0.52), and Asia (10%; 95% CI, 0.02-0.32). The extensive use of polymyxins on veterinary to control bacterial infection and growth promotion, as well as the resurgence in prescription and use of polymyxins in the clinics against carbapenem-resistant gram-negative bacteria, may have contributed to the increased incidence of PRAB. The findings of this meta-analysis revealed that the rate of PRAB recovered from hospitalized patients is distinctively high. Thus, action needs to be taken to develop strategies to combat the clinical incidence of PRAB-induced hospital infections.pt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ALIMENTOSpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofEuropean Journal of Clinical Microbiology & Infectious Diseasespt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectAcinetobacter baumanniipt_BR
dc.subjectCarbapenem resistantpt_BR
dc.subjectColistinpt_BR
dc.subjectHospital infectionspt_BR
dc.subjectPolymyxin B.pt_BR
dc.subject.otherPolimixinaspt_BR
dc.subject.otherAcinetobacter baumanniipt_BR
dc.subject.otherPacientespt_BR
dc.subject.otherRevisão sistemáticapt_BR
dc.subject.otherMetanálisept_BR
dc.titleRate of polymyxin resistance among Acinetobacter baumannii recovered from hospitalized patients: a systematic review and meta-analysispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s10096-020-03876-xpt_BR
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