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http://hdl.handle.net/1843/41938
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DC Field | Value | Language |
---|---|---|
dc.creator | William Gustavo Lima | pt_BR |
dc.creator | Júlio César Moreira Brito | pt_BR |
dc.creator | Bárbara Gatti Cardoso | pt_BR |
dc.creator | Valbert Nascimento Cardoso | pt_BR |
dc.creator | Magna Cristina de Paiva | pt_BR |
dc.creator | Maria Elena de Lima | pt_BR |
dc.creator | Simone Odília Antunes Fernandes | pt_BR |
dc.date.accessioned | 2022-05-24T21:50:42Z | - |
dc.date.available | 2022-05-24T21:50:42Z | - |
dc.date.issued | 2020 | - |
dc.citation.volume | 39 | pt_BR |
dc.citation.issue | 8 | pt_BR |
dc.citation.spage | 1427 | pt_BR |
dc.citation.epage | 1438 | pt_BR |
dc.identifier.doi | 10.1007/s10096-020-03876-x | pt_BR |
dc.identifier.issn | 0934-9723 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/41938 | - |
dc.description.resumo | We conducted a systematic review and meta-analysis to determine the rate of polymyxin resistance among Acinetobacter baumannii isolates causing infection in hospitalized patients around the world during the period of 2010-2019. The systematic review was performed on September 1, 2019, using PubMed/MEDLINE, Scopus, and Web of Science; studies published after January 1, 2010, were selected. The data were summarized in tables, critically analyzed, and treated statistically using the RStudio® Software with Meta package and Metaprop Command. After applying exclusion factors, 41 relevant studies were selected from 969 articles identified on literature search. The overall rate of polymyxin-resistant A. baumannii (PRAB) related to hospitalized patients was estimated to be 13% (95% CI, 0.06-0.27), where a higher rate was observed in America (29%; 95% CI, 0.12-0.55), followed by Europe (13%; 95% CI, 0.02-0.52), and Asia (10%; 95% CI, 0.02-0.32). The extensive use of polymyxins on veterinary to control bacterial infection and growth promotion, as well as the resurgence in prescription and use of polymyxins in the clinics against carbapenem-resistant gram-negative bacteria, may have contributed to the increased incidence of PRAB. The findings of this meta-analysis revealed that the rate of PRAB recovered from hospitalized patients is distinctively high. Thus, action needs to be taken to develop strategies to combat the clinical incidence of PRAB-induced hospital infections. | pt_BR |
dc.description.sponsorship | CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior | pt_BR |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | FAR - DEPARTAMENTO DE ALIMENTOS | pt_BR |
dc.publisher.department | FAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICAS | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | European Journal of Clinical Microbiology & Infectious Diseases | pt_BR |
dc.rights | Acesso Restrito | pt_BR |
dc.subject | Acinetobacter baumannii | pt_BR |
dc.subject | Carbapenem resistant | pt_BR |
dc.subject | Colistin | pt_BR |
dc.subject | Hospital infections | pt_BR |
dc.subject | Polymyxin B. | pt_BR |
dc.subject.other | Polimixinas | pt_BR |
dc.subject.other | Acinetobacter baumannii | pt_BR |
dc.subject.other | Pacientes | pt_BR |
dc.subject.other | Revisão sistemática | pt_BR |
dc.subject.other | Metanálise | pt_BR |
dc.title | Rate of polymyxin resistance among Acinetobacter baumannii recovered from hospitalized patients: a systematic review and meta-analysis | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | https://link.springer.com/article/10.1007/s10096-020-03876-x | pt_BR |
Appears in Collections: | Artigo de Periódico |
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