1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/42073
Full metadata record
DC FieldValueLanguage
dc.creatorMichele Munk Pereirapt_BR
dc.creatorHumberto de Mello Brandãopt_BR
dc.creatorLuiz Sérgio de Almeida Camargopt_BR
dc.creatorCarolina Capobiango Romano Quintãopt_BR
dc.creatorSaulo R. Silvapt_BR
dc.creatorEliza Diniz de Souzapt_BR
dc.creatorNádia Rezende Barbosa Raposopt_BR
dc.creatorJosé Manoel Marconcinipt_BR
dc.creatorAdo Jorio de Vasconcelospt_BR
dc.creatorLuiz Orlando Ladeirapt_BR
dc.date.accessioned2022-05-30T16:25:18Z-
dc.date.available2022-05-30T16:25:18Z-
dc.date.issued2016-
dc.citation.volume12pt_BR
dc.citation.issue5pt_BR
dc.citation.spage1151pt_BR
dc.citation.epage1159pt_BR
dc.identifier.doi10.1016/j.nano.2016.01.006pt_BR
dc.identifier.issn1549-9634pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/42073-
dc.description.resumoCurrently there is a growing interest in the use of nanotechnology in reproductive medicine and reproductive biology. However, their toxic effects on mammalian embryos remain poorly understood. In this work, we evaluate the biocompatibility of two fibrous nanomaterials (NMs): cotton cellulose nanofibers (CNF) and carboxylated multiwalled carbon nanotubes (MWCNT-COOH), by performing an investigation of the embryonic development, gene expression (biomarkers focused on cell stress, apoptosis and totipotency) and in situ apoptosis in bovine embryos. Exposure to NMs did not interfere in preimplantation development or in the incidence of apoptosis in the bovine embryo, but they did affect the gene expression. The results presented are important for an understanding of the toxicity of cotton CNF and MWCNT-COOH on mammalian embryos. To our knowledge, we report the first evaluation of biocompatibility between these NMs on preimplantation embryos, which may open a new window for reproductive biomedical applications.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE FÍSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofNanomedicine: Nanotechnology, Biology and Medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectFibrous nanomaterialspt_BR
dc.subjectBiocompatibilitypt_BR
dc.subjectGene expressionpt_BR
dc.subjectApoptosispt_BR
dc.subject.otherNanomateriaispt_BR
dc.subject.otherBiocompatibilidadept_BR
dc.subject.otherApoptosept_BR
dc.titleBiocompatibility assessment of fibrous nanomaterials in mammalian embryospt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S1549963416000769?via%3Dihubpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8927-6190pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-7405-3928pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9974-711Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6232-2174pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-5271-1048pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-0419-9796pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5978-2735pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-4935-6070pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
There are no files associated with this item.
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.