Cross-talk between obesity and central nervous system: role in cognitive function

Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/43028

Tipo:	Artigo de Periódico
Título:	Cross-talk between obesity and central nervous system: role in cognitive function
Autor(es):	Ricardo Augusto Leoni de Sousa Daniel de Almeida Freitas Hércules Ribeiro Leite
Resumo:	Obesity is a world health problem. Excess of white adipose tissue (WAT) might lead to development of neurodegenerative disorders. WAT contributes to low-grade inflammation leading to the enhancement of pro-inflammatory adipokines, such as TNF-α, leptin and IL-6, which will lead to a peripheral inflammation that affects central nervous system functioning. Pro-inflammatory adipokines are enhanced in obesity, while anti-inflammatory, such as IL-10 and adiponectin, are reduced. Obesity seems to be related to cognitive decline and the development of neurodegenerative diseases, such as dementia and Alzheimer, through the production of pro-inflammatory adipokines with a consistent reduction of adiponectin and IL-10.
Assunto:	Obesidade Inflamação Leptina Cérebro Sistema nervoso central Cognição
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Instituição:	UFMG
Departamento:	EEF - DEPARTAMENTO DE FISIOTERAPIA
Tipo de Acesso:	Acesso Aberto
Identificador DOI:	http://dx.doi.org/10.31031/iod.2019.03.000551
URI:	http://hdl.handle.net/1843/43028
Data do documento:	Jun-2019
metadata.dc.url.externa:	https://crimsonpublishers.com/iod/fulltext/IOD.000551.php
metadata.dc.relation.ispartof:	Intervention in Obesity and Diabetes
Aparece nas coleções:	Artigo de Periódico

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