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http://hdl.handle.net/1843/43028
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Campo DC | Valor | Idioma |
---|---|---|
dc.creator | Ricardo Augusto Leoni de Sousa | pt_BR |
dc.creator | Daniel de Almeida Freitas | pt_BR |
dc.creator | Hércules Ribeiro Leite | pt_BR |
dc.date.accessioned | 2022-07-07T16:45:57Z | - |
dc.date.available | 2022-07-07T16:45:57Z | - |
dc.date.issued | 2019-06 | - |
dc.citation.volume | 3 | pt_BR |
dc.citation.issue | 1 | pt_BR |
dc.citation.spage | 214 | pt_BR |
dc.citation.epage | 216 | pt_BR |
dc.identifier.doi | http://dx.doi.org/10.31031/iod.2019.03.000551 | pt_BR |
dc.identifier.issn | 2578-0263 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/43028 | - |
dc.description.resumo | Obesity is a world health problem. Excess of white adipose tissue (WAT) might lead to development of neurodegenerative disorders. WAT contributes to low-grade inflammation leading to the enhancement of pro-inflammatory adipokines, such as TNF-α, leptin and IL-6, which will lead to a peripheral inflammation that affects central nervous system functioning. Pro-inflammatory adipokines are enhanced in obesity, while anti-inflammatory, such as IL-10 and adiponectin, are reduced. Obesity seems to be related to cognitive decline and the development of neurodegenerative diseases, such as dementia and Alzheimer, through the production of pro-inflammatory adipokines with a consistent reduction of adiponectin and IL-10. | pt_BR |
dc.format.mimetype | pt_BR | |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | EEF - DEPARTAMENTO DE FISIOTERAPIA | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | Intervention in Obesity and Diabetes | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | Obesity | pt_BR |
dc.subject | Inflammation | pt_BR |
dc.subject | Leptin | pt_BR |
dc.subject | Brain regions | pt_BR |
dc.subject | Cognitive performance | pt_BR |
dc.subject.other | Obesidade | pt_BR |
dc.subject.other | Inflamação | pt_BR |
dc.subject.other | Leptina | pt_BR |
dc.subject.other | Cérebro | pt_BR |
dc.subject.other | Sistema nervoso central | pt_BR |
dc.subject.other | Cognição | pt_BR |
dc.title | Cross-talk between obesity and central nervous system: role in cognitive function | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | https://crimsonpublishers.com/iod/fulltext/IOD.000551.php | pt_BR |
dc.identifier.orcid | https://orcid.org/ 0000-0003-2622-032X | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-8977-8131 | pt_BR |
Aparece en las colecciones: | Artigo de Periódico |
archivos asociados a este elemento:
archivo | Descripción | Tamaño | Formato | |
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Cross Talk Between Obesity and Central Nervous System.pdf | 318.39 kB | Adobe PDF | Visualizar/Abrir |
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