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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/43028
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dc.creatorRicardo Augusto Leoni de Sousapt_BR
dc.creatorDaniel de Almeida Freitaspt_BR
dc.creatorHércules Ribeiro Leitept_BR
dc.date.accessioned2022-07-07T16:45:57Z-
dc.date.available2022-07-07T16:45:57Z-
dc.date.issued2019-06-
dc.citation.volume3pt_BR
dc.citation.issue1pt_BR
dc.citation.spage214pt_BR
dc.citation.epage216pt_BR
dc.identifier.doihttp://dx.doi.org/10.31031/iod.2019.03.000551pt_BR
dc.identifier.issn2578-0263pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/43028-
dc.description.resumoObesity is a world health problem. Excess of white adipose tissue (WAT) might lead to development of neurodegenerative disorders. WAT contributes to low-grade inflammation leading to the enhancement of pro-inflammatory adipokines, such as TNF-α, leptin and IL-6, which will lead to a peripheral inflammation that affects central nervous system functioning. Pro-inflammatory adipokines are enhanced in obesity, while anti-inflammatory, such as IL-10 and adiponectin, are reduced. Obesity seems to be related to cognitive decline and the development of neurodegenerative diseases, such as dementia and Alzheimer, through the production of pro-inflammatory adipokines with a consistent reduction of adiponectin and IL-10.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofIntervention in Obesity and Diabetespt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectObesitypt_BR
dc.subjectInflammationpt_BR
dc.subjectLeptinpt_BR
dc.subjectBrain regionspt_BR
dc.subjectCognitive performancept_BR
dc.subject.otherObesidadept_BR
dc.subject.otherInflamaçãopt_BR
dc.subject.otherLeptinapt_BR
dc.subject.otherCérebropt_BR
dc.subject.otherSistema nervoso centralpt_BR
dc.subject.otherCogniçãopt_BR
dc.titleCross-talk between obesity and central nervous system: role in cognitive functionpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://crimsonpublishers.com/iod/fulltext/IOD.000551.phppt_BR
dc.identifier.orcidhttps://orcid.org/ 0000-0003-2622-032Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-8977-8131pt_BR
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