Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/43028| Type: | Artigo de Periódico |
| Title: | Cross-talk between obesity and central nervous system: role in cognitive function |
| Authors: | Ricardo Augusto Leoni de Sousa Daniel de Almeida Freitas Hércules Ribeiro Leite |
| Abstract: | Obesity is a world health problem. Excess of white adipose tissue (WAT) might lead to development of neurodegenerative disorders. WAT contributes to low-grade inflammation leading to the enhancement of pro-inflammatory adipokines, such as TNF-α, leptin and IL-6, which will lead to a peripheral inflammation that affects central nervous system functioning. Pro-inflammatory adipokines are enhanced in obesity, while anti-inflammatory, such as IL-10 and adiponectin, are reduced. Obesity seems to be related to cognitive decline and the development of neurodegenerative diseases, such as dementia and Alzheimer, through the production of pro-inflammatory adipokines with a consistent reduction of adiponectin and IL-10. |
| Subject: | Obesidade Inflamação Leptina Cérebro Sistema nervoso central Cognição |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | EEF - DEPARTAMENTO DE FISIOTERAPIA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | http://dx.doi.org/10.31031/iod.2019.03.000551 |
| URI: | http://hdl.handle.net/1843/43028 |
| Issue Date: | Jun-2019 |
| metadata.dc.url.externa: | https://crimsonpublishers.com/iod/fulltext/IOD.000551.php |
| metadata.dc.relation.ispartof: | Intervention in Obesity and Diabetes |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Cross Talk Between Obesity and Central Nervous System.pdf | 318.39 kB | Adobe PDF | View/Open |
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