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http://hdl.handle.net/1843/44674| Type: | Artigo de Periódico |
| Title: | Antimicrobial activity, effects on streptococcus mutans biofilm and interfacial bonding of adhesive systems with and without antibacterial agent |
| Authors: | Carolina Bosso André Brenda Paula Figueiredo Almeida Gomes Thais Mageste Duque Pedro Luiz Rosalen Daniel Chi Ngai Chan Glaucia Maria Bovi Ambrosano Marcelo Giannini |
| Abstract: | Objectives This study evaluated the antimicrobial activity (by agar disk diffusion test, AD), viability of S. mutans biofilm (VB), and effect on resin-dentin interface (RDI) of six adhesive systems. Methods Three adhesives containing antibacterial components (Gluma 2Bond (G2B)/glutaraldehyde, Clearfil SE Protect (CSP)/MDPB and Peak Universal Bond (PUB)/chlorhexidine) and the corresponding adhesives with similar composition, but without antibacterial agents (Gluma Comfort Bond, GCB; Clearfil SE Bond, CSB and Peak LC Bond, PLB) were evaluated. AD was determined measuring the extent of halo formation following application of adhesives and control groups (light cured or not) to cultures of four strict anaerobic and four facultative bacteria. For VB, a UA159 biofilm was grown on adhesive-coated hydroxyapatite discs for five days, collected and processed to count the number of viable cells. For RDI analysis, adhesives were applied according to manufacturers' recommendations and teeth were restored with resin composite, sectioned to obtain bonded slices and visualized by SEM. Results An inhibition halo was observed for G2B (strict anaerobic/light cured and not light cured), CSP (strict anaerobic and facultative/light cured and not light cured) and PUB (strict anaerobic and facultative/not light cured). PUB when light cured produced an inhibition halo on L. casei and S. mutans only. G2B and CSP significantly reduced the viability of S. mutans. Adhesives containing antimicrobial compounds had no detectable effect on RDI. Conclusion The MDPB-containing bonding agent showed better results of inhibition for all oral pathogens tested and a decrease of viability of Streptococcus mutans biofilm, among the adhesives tested |
| Subject: | Anti-infective agents Dentin-bonding agents Biofilms Streptococcus mutans |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | 10.1016/j.ijadhadh.2016.10.011 |
| URI: | http://hdl.handle.net/1843/44674 |
| Issue Date: | Jan-2017 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S014374961630207X |
| metadata.dc.relation.ispartof: | International Journal of Adhesion and Adhesives |
| Appears in Collections: | Artigo de Periódico |
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