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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/44766
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dc.creatorFábio Ribeiro Santospt_BR
dc.creatorAmanda Souto Machadopt_BR
dc.creatorDeborah Farias Lelispt_BR
dc.creatorAndré Luiz Sena Guimarãespt_BR
dc.creatorAlfredo Maurício Batista de Paulapt_BR
dc.creatorRenato Sobral Monteiro Júniorpt_BR
dc.creatorTheles de Oliveira Costapt_BR
dc.creatorIgor Viana Brandipt_BR
dc.creatorJúnio Cota Silvapt_BR
dc.creatorSergio Henrique Sousa Santospt_BR
dc.date.accessioned2022-08-31T14:22:56Z-
dc.date.available2022-08-31T14:22:56Z-
dc.date.issued2020-11-24-
dc.citation.volume8pt_BR
dc.citation.issue3pt_BR
dc.citation.spage1148pt_BR
dc.identifier.issn2381-8980pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/44766-
dc.description.resumoScope: this study has a novel approach to investigate the effects of oral supplementation of kefir grains on metabolic improvement and the expression of the antioxidant enzymes Glutathione Peroxidase (GPx) and Catalase (CAT) of the liver in malnourished mice. Method and results: swiss mice were divided into four groups and subjected to two treatment phases: the food restriction phase of 20% in relation to the control group was maintained until animals reached a weight deficit of about 20% in relation to their original weight and the renutrition phase, the animals received diets every day for 30 days. Diets (chow powder plus kefir grains) were administered orally. Thereafter, during throughout the experiment measurements of body weight and energy consumption were obtained. After the end of treatment, fasting glucose tolerance tests were performed at night and insulin sensitivity with fed mice. Soon in then, the mice were euthanized by beheading in guillotine and the blood and liver were collected for evaluation of biochemical parameters, Histopathological assessments and Reverse transcriptase (RT-PCR). Conclusion: the present study demonstrated the kefir grains ability to modulate inflammation and hepatic oxidative-stress under malnourished-state.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofAustin Journal of Nutrition and Food Sciencespt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherDieta de baixa caloriapt_BR
dc.subject.otherDesnutriçãopt_BR
dc.subject.otherStress oxidativopt_BR
dc.subject.otherKefirpt_BR
dc.titleOral kefir grains supplementation improves metabolism and liver antioxidant enzymes expression in malnourished micept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://austinpublishinggroup.com/nutrition-food-sciences/fulltext/ajnfs-v8-id1148.pdfpt_BR
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