Might anxiety disorders promote head and neck cancer development?

Marcela Gonçalvesde Souza; Emisael Stênio Batista Gomes; Lorena Barbosa Costa; Amanda Dias Silva Andrade; Sabrina Ferreira de Jesus; Daniela Paola Santos de Paula; Rogério Gonçalves da Rocha; Sérgio Henrique Sousa Santos; Alfredo Maurício Batista de Paula; Lucyana Conceição Farias; André Luiz Sena Guimarães

Use este identificador para citar ou linkar para este item: http://hdl.handle.net/1843/44946

Tipo:	Artigo de Periódico
Título:	Might anxiety disorders promote head and neck cancer development?
Autor(es):	Marcela Gonçalvesde Souza Emisael Stênio Batista Gomes Lorena Barbosa Costa Amanda Dias Silva Andrade Sabrina Ferreira de Jesus Daniela Paola Santos de Paula Rogério Gonçalves da Rocha Sérgio Henrique Sousa Santos Alfredo Maurício Batista de Paula Lucyana Conceição Farias André Luiz Sena Guimarães
Resumo:	Cancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma.
Assunto:	Transtornos da ansiedade Cabeça - Câncer Pescoço - Câncer Carcinoma de células escamosas Tumores
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Instituição:	UFMG
Departamento:	ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
Tipo de Acesso:	Acesso Aberto
Identificador DOI:	https://doi.org/10.1016/j.ibror.2020.06.001
URI:	http://hdl.handle.net/1843/44946
Data do documento:	Dez-2020
metadata.dc.url.externa:	https://www.sciencedirect.com/science/article/pii/S2451830120300169
metadata.dc.relation.ispartof:	IBRO Reports
Aparece nas coleções:	Artigo de Periódico

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