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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/44946
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dc.creatorMarcela Gonçalvesde Souzapt_BR
dc.creatorEmisael Stênio Batista Gomespt_BR
dc.creatorLorena Barbosa Costapt_BR
dc.creatorAmanda Dias Silva Andradept_BR
dc.creatorSabrina Ferreira de Jesuspt_BR
dc.creatorDaniela Paola Santos de Paulapt_BR
dc.creatorRogério Gonçalves da Rochapt_BR
dc.creatorSérgio Henrique Sousa Santospt_BR
dc.creatorAlfredo Maurício Batista de Paulapt_BR
dc.creatorLucyana Conceição Fariaspt_BR
dc.creatorAndré Luiz Sena Guimarãespt_BR
dc.date.accessioned2022-09-06T14:09:10Z-
dc.date.available2022-09-06T14:09:10Z-
dc.date.issued2020-12-
dc.citation.volume9pt_BR
dc.citation.spage9pt_BR
dc.citation.epage13pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.ibror.2020.06.001pt_BR
dc.identifier.issn2451-8301pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/44946-
dc.description.resumoCancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofIBRO Reportspt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherTranstornos da ansiedadept_BR
dc.subject.otherCabeça - Câncerpt_BR
dc.subject.otherPescoço - Câncerpt_BR
dc.subject.otherCarcinoma de células escamosaspt_BR
dc.subject.otherTumorespt_BR
dc.titleMight anxiety disorders promote head and neck cancer development?pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S2451830120300169pt_BR
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