Use este identificador para citar ou linkar para este item:
http://hdl.handle.net/1843/46342
Tipo: | Artigo de Evento |
Título: | Quality of life of people living with HIV/AIDS initiating antiretroviral therapy in the single tablet regimen era |
Autor(es): | Juliana Oliveira Costa Maria Das Graças Braga Ceccato Celline Cardoso Almeida Brasil Romara Elizeu Amaro Perdigão Micheline Rosa Silveira Palmira de Fátima Bonolo Francisco de Assis Acurcio |
Resumo: | Background: Antiretroviral therapy (ART) has increased life expectancy of people living with HIV/ AIDS (PLHA). Single tablet regimens (STR) contributed to increase patient’s adherence to ART, but its influence in the quality of life (QoL) is still unknown. Objectives: To outline the profile and assess the QoL and associated factors of patients initiating ART in a reference hospital in Belo Horizonte, Brazil. Methods: Baseline evaluation of a cohort of 184 patients initiating ART between Sep/2015 and Aug/ 2016. We obtained sociodemographic, clinical and behavioral data through face-to-face interviews and used EuroQol5D-3L (EQ5D) and WHOQoLHIVbref instruments to assess QoL. We used non-parametric tests to compare QoL within groups using SPPS v21. Results: Patients were mainly men (79%), mean age of 35.9 ± 11.6 years old, unmarried (75%), nonbrowns (51%), had 9+ years of schooling (71%), were employed (81%) and with family income between 205 and 773 dollars (70%). In addition, 47% had children and 21% had health insurance. The majority was religious (78%) and had experienced in their lives alcohol (82%), tobacco (53%) or illicit drugs (46%). Median time of diagnosis and treatment was five and two months, respectively. Signs and symptoms of anxiety occurred in 37% of patients and of depression in 27%. About 84% used STR, 46% were adherent to ART and 75% reported at least one adverse reaction. Patients showed a good QoL in both instruments: EQ5D index (0.842 ± 0.146) and VAS (73.62 ± 21.3%). Average values of WHOQoLHIV-bref domains were 15.1 ± 3.2 (physical), 14.7 ± 2.8 (psychological), 14.7 ± 2.9 (independence), 14.7 ± 3.1 (social), 13.9 ± 2.5 (environment) and 14.5 ± 3.7 (spirituality). Patients in STR had higher Qol in EQ5D index (p = 0.02), VAS (p = 0.03) and in the WHOQoLHIV-bref independence domain (p < 0.01). Other factors influenced at least one domain: sex, age, marital status, schooling, health insurance, family income, religiousness, use of tobacco, signs and symptoms of anxiety and depression, time of treatment and of diagnosis, adverse reaction and adherence. Conclusions: QoL is influenced by the type of ART regimen and other sociodemographic, clinical and behavioral characteristics. This knowledge is useful to guide interventions to improve QoL of PLHA initiating ART. |
Assunto: | HIV AIDS Terapia antirretroviral |
Idioma: | eng |
País: | Brasil |
Editor: | Universidade Federal de Minas Gerais |
Sigla da Instituição: | UFMG |
Departamento: | FAR - DEPARTAMENTO DE FARMÁCIA SOCIAL |
Tipo de Acesso: | Acesso Aberto |
Identificador DOI: | https://doi.org/10.1002/pds.4275 |
URI: | http://hdl.handle.net/1843/46342 |
Data do documento: | 22-Ago-2017 |
metadata.dc.url.externa: | https://onlinelibrary.wiley.com/doi/full/10.1002/pds.4275 |
metadata.dc.relation.ispartof: | International Conference on Pharmacoepidemiology & Therapeutic Risk Management |
Aparece nas coleções: | Artigo de Evento |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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Quality of life of people living with hiv aids initiating antiretroviral therapy in the single tablet regimen era.pdf | 66.71 kB | Adobe PDF | Visualizar/Abrir |
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