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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/46342
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dc.creatorJuliana Oliveira Costapt_BR
dc.creatorMaria Das Graças Braga Ceccatopt_BR
dc.creatorCelline Cardoso Almeida Brasilpt_BR
dc.creatorRomara Elizeu Amaro Perdigãopt_BR
dc.creatorMicheline Rosa Silveirapt_BR
dc.creatorPalmira de Fátima Bonolopt_BR
dc.creatorFrancisco de Assis Acurciopt_BR
dc.date.accessioned2022-10-18T22:03:06Z-
dc.date.available2022-10-18T22:03:06Z-
dc.date.issued2017-08-22-
dc.citation.issue33pt_BR
dc.citation.spage152pt_BR
dc.citation.epage153pt_BR
dc.identifier.doihttps://doi.org/10.1002/pds.4275pt_BR
dc.identifier.issn1099-1557pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/46342-
dc.description.resumoBackground: Antiretroviral therapy (ART) has increased life expectancy of people living with HIV/ AIDS (PLHA). Single tablet regimens (STR) contributed to increase patient’s adherence to ART, but its influence in the quality of life (QoL) is still unknown. Objectives: To outline the profile and assess the QoL and associated factors of patients initiating ART in a reference hospital in Belo Horizonte, Brazil. Methods: Baseline evaluation of a cohort of 184 patients initiating ART between Sep/2015 and Aug/ 2016. We obtained sociodemographic, clinical and behavioral data through face-to-face interviews and used EuroQol5D-3L (EQ5D) and WHOQoLHIVbref instruments to assess QoL. We used non-parametric tests to compare QoL within groups using SPPS v21. Results: Patients were mainly men (79%), mean age of 35.9 ± 11.6 years old, unmarried (75%), nonbrowns (51%), had 9+ years of schooling (71%), were employed (81%) and with family income between 205 and 773 dollars (70%). In addition, 47% had children and 21% had health insurance. The majority was religious (78%) and had experienced in their lives alcohol (82%), tobacco (53%) or illicit drugs (46%). Median time of diagnosis and treatment was five and two months, respectively. Signs and symptoms of anxiety occurred in 37% of patients and of depression in 27%. About 84% used STR, 46% were adherent to ART and 75% reported at least one adverse reaction. Patients showed a good QoL in both instruments: EQ5D index (0.842 ± 0.146) and VAS (73.62 ± 21.3%). Average values of WHOQoLHIV-bref domains were 15.1 ± 3.2 (physical), 14.7 ± 2.8 (psychological), 14.7 ± 2.9 (independence), 14.7 ± 3.1 (social), 13.9 ± 2.5 (environment) and 14.5 ± 3.7 (spirituality). Patients in STR had higher Qol in EQ5D index (p = 0.02), VAS (p = 0.03) and in the WHOQoLHIV-bref independence domain (p < 0.01). Other factors influenced at least one domain: sex, age, marital status, schooling, health insurance, family income, religiousness, use of tobacco, signs and symptoms of anxiety and depression, time of treatment and of diagnosis, adverse reaction and adherence. Conclusions: QoL is influenced by the type of ART regimen and other sociodemographic, clinical and behavioral characteristics. This knowledge is useful to guide interventions to improve QoL of PLHA initiating ART.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Conference on Pharmacoepidemiology & Therapeutic Risk Managementpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectHIVpt_BR
dc.subjectAIDSpt_BR
dc.subjectTerapia antirretroviralpt_BR
dc.subject.otherHIVpt_BR
dc.subject.otherAIDSpt_BR
dc.subject.otherTerapia antirretroviralpt_BR
dc.titleQuality of life of people living with HIV/AIDS initiating antiretroviral therapy in the single tablet regimen erapt_BR
dc.typeArtigo de Eventopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/full/10.1002/pds.4275pt_BR
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