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Type:	Artigo de Periódico
Title:	Bleaching gel mixed with MI paste plus reduces penetration of H2O2 and damage to pulp tissue and maintains bleaching effectiveness
Authors:	Jéssica Galbiati Barbosa Francine Benetti Marjorie de Oliveira Gallinari Marina Carminatti Anna Beatriz Dias da Silva Isabela Nakahara Ikeda Lopes André Luiz Fraga Briso Luciano Tavares Ângelo Cintra
Abstract:	Objectives: MI Paste Plus remineralizer (Rem) strengthens dental structures after bleaching. We investigated the effect of Rem on the penetration of hydrogen peroxide (H2O2), bleaching effectiveness, and pulp inflammation after bleaching. Materials and methods: Bovine disks were grouped as follows (n = 10): control (untreated), bleached (Ble; 35% H2O2, 30 min), Ble-Rem (H2O2 followed by Rem, 30 min), Rem-Ble (Rem followed by H2O2), Rem-Ble-Rem (Rem before and after H2O2), and Ble+Rem (mixture of Rem with H2O2, 1:1, 30 min). The penetration of H2O2 was quantified and bleaching efficacy was analyzed. Upper rat molars (n = 10) received the same treatments at random. The rats were euthanized after two days and 30 days, and their jaws were removed for histological analysis. Statistical tests were performed (P < 0.05). Results: The bleached groups, except Ble+Rem (P > 0.05), showed significant H2O2 penetration compared with control (P < 0.05). Color alteration analysis showed that ΔL and ΔE were significantly higher in the bleached groups than those in control (P < 0.05); the Δb of the bleached groups differed from that of control at 24 h (P < 0.05). At two days, necrosis or inflammation was observed in the bleached groups compared with control (P < 0.05), except Ble+Rem, which was similar to control (P > 0.05). At 30 days, tertiary dentin formation was significant in the bleached groups (P < 0.05), except Ble+Rem (P > 0.05). Conclusion: The mixture of MI Paste Plus and bleaching gel reduces H2O2 penetration and pulp damage and maintains bleaching effectiveness. Clinical relevance: Because bleaching can damage dental tissues, we studied a new bleaching protocol that reduces damage to the pulp tissue while maintaining bleaching efficiency: a single application of 30 min of MI Paste Plus mixed with 35% H2O2 bleaching gel (1:1)
Subject:	Tooth bleaching Hydrogen peroxide Molar Dentin
language:	eng
metadata.dc.publisher.country:	Brasil
Publisher:	Universidade Federal de Minas Gerais
Publisher Initials:	UFMG
metadata.dc.publisher.department:	FAO - DEPARTAMENTO DE ODONTOLOGIA RESTAURADORA
Rights:	Acesso Restrito
metadata.dc.identifier.doi:	https://doi.org/10.1007/s00784-019-03009-5
URI:	http://hdl.handle.net/1843/47499
Issue Date:	13-Jul-2019
metadata.dc.url.externa:	https://link.springer.com/article/10.1007/s00784-019-03009-5
metadata.dc.relation.ispartof:	Clinical Oral Investigations
Appears in Collections:	Artigo de Periódico

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