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http://hdl.handle.net/1843/47845| Type: | Artigo de Periódico |
| Title: | Control of Haemonchus contortus in sheep using basidiocarps of Agaricus blazei Murril |
| Authors: | Thallyta Maria Vieira Leydiana Duarte Fonseca Gabriela Almeida Bastos Viviane de Oliveira Vasconcelos Maria Luiza França Silva Franciellen Morais Costa Adriano Vinicius de Paiva Ferreira Neide Judith Faria de Oliveira Eduardo Robson Duarte |
| Abstract: | Objective: this study evaluated the effects in vitro and in vivo of Agaricus blazei against Haemonchus contortus in sheep. Methods: the in vitro efficacy of aqueous extract on egg hatching inhibition (EHI) was investigated and after 72 h incubation with varying concentrations the effects on, blastomeres, embryonated eggs, and first stage larvae (L1) were evaluated. Larval development inhibition (LDI) for dry powder and the aqueous extract were evaluated in fecal cultures of sheep infected with H. contortus. In vivo efficacy was determined by reduction in fecal egg count (FEC). Lambs were treated with powder A. blazei (11.4 g/kg pc) or trichlorfon, or were untreated and the possible toxicity of this fungus was monitored by plasmatic enzyme analysis. Results: concentrations equal to and higher than 3.62 mg/mL and of aqueous extract were 100% effective in the EHI test. In the LDI test, LC90 was estimated for 5.66 and 106.0 mg/g fecal culture for aqueous extract and powder, respectively. The mean FEC in lambs 14 days post-treatment with A. blazei powder was significantly lower than observed for the negative control, and the serum levels of aspartate transaminase and alanine transaminase were normal. Conclusion: the fungi supplementation promotes, respectively, high and moderate anthelmintic efficacy with in vitro and in vivo tests, respectively, suggesting it as an alternative or complementary treatment for haemonchosis in sheep. |
| Subject: | Haemonchus contortus Basidiomicetos Ovinos - Doenças |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | 10.1007/s11259-017-9677-x |
| URI: | http://hdl.handle.net/1843/47845 |
| Issue Date: | 31-Jan-2017 |
| metadata.dc.url.externa: | https://link.springer.com/article/10.1007/s11259-017-9677-x |
| metadata.dc.relation.ispartof: | Veterinary Research Communications |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Anthelmintic activity of Annona crassiflora leaves against Haemonchus contortus.pdf | 287.95 kB | Adobe PDF | View/Open |
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