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http://hdl.handle.net/1843/48831
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DC Field | Value | Language |
---|---|---|
dc.creator | Joao Marcus Oliveira Andrade | pt_BR |
dc.creator | Deborah de Farias Lelis | pt_BR |
dc.creator | Valeria Mafra Cota | pt_BR |
dc.creator | Júnio Cota Silva | pt_BR |
dc.date.accessioned | 2023-01-10T18:32:57Z | - |
dc.date.available | 2023-01-10T18:32:57Z | - |
dc.date.issued | 2017 | - |
dc.citation.volume | 24 | pt_BR |
dc.citation.issue | 9 | pt_BR |
dc.citation.spage | 827 | pt_BR |
dc.citation.epage | 832 | pt_BR |
dc.identifier.issn | 1875-5305 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/48831 | - |
dc.description.resumo | Background: The renin-angiotensin system (RAS) is an important enzymatic system responsible for the regulation of biological functions, such as the arterial pressure, hydroelectrolytic control, vascular vasodilatation/vasoconstriction and more recently metabolic functions. Objectives: The aim of the present review is to discuss the associations between the gut microbiome and the renin-angiotensin system and the influence of their intimate relationship on the cardiovascular health. Methods: A literature review of the main studies published regarding the relationship among the renin-angiotensin system, gut microbiota and cardiovascular health was performed. Results: The association between the ACE2 and gut microbiota has been discussed. It is shown that the ACE2/Ang 1-7 axis modulates the immune response, influencing the microbiota composition, and thus being one of the causes for some diseases physiophatologies, such as diarrhea and intestinal inflammatory disease. Conclusion: The association between RAS and gut microbiota seems to have a strong influence on the genesis of cardiovascular diseases, through direct mechanisms, such as nerve stimulation, or indirectly on metabolic parameters, such as weight, adiposity and lipid profile. | pt_BR |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | Protein & Peptide Letters | pt_BR |
dc.rights | Acesso Restrito | pt_BR |
dc.subject | Renin-angiotensin system | pt_BR |
dc.subject | Angiotensin converting enzyme 2 | pt_BR |
dc.subject | Gut microbiota | pt_BR |
dc.subject | Cardiovascular health | pt_BR |
dc.subject.other | Enzima conversora da angiotensina | pt_BR |
dc.subject.other | Sistema cardiovascular | pt_BR |
dc.title | The angiotensin converting enzyme 2 (ACE2), gut microbiota, and cardiovascular health | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | http://www.eurekaselect.com/article/85062 | pt_BR |
Appears in Collections: | Artigo de Periódico |
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