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http://hdl.handle.net/1843/48956| Type: | Artigo de Periódico |
| Title: | Use of exhaled air as an improved biomonitoring method to assess perchloroethylene short-term exposure |
| Authors: | Claúdia Maria Dias Paes Helvécio Costa Menezes Zenilda de Lourdes Cardeal |
| Abstract: | This paper shows the use of exhaled air as a biomonitoring method to assess perchloroethylene (PERC) environmental and occupational exposure. A sensitive, fast, and solvent free analytical method was developed to determine PERC in ambient and exhaled air of individuals occupationally exposed. The developed method used cold fiber solid phase microextraction (CF-SPME) as the sampling technique, and a standard permeation method to simulation of air matrix. The analysis were conducted by gas chromatography coupled to mass spectrometry (GC/MS). The methods were validated and were found to be precise, linear and sensitive for environmental and biological monitoring. The developed methods were applied to twenty-seven sampling points spread across Belo Horizonte city, Brazil, twenty four dry cleaners, an electroplating industry, a research laboratory, and an automotive paint preparation shop. The results of ambient air analyses ranging from 14.0 to 3205.0 µg m−³ with median concentration of 599.0 µg m−³. Furthermore, sampling of exhaled air of individuals occupationally exposed presented results ranging from 6.0 to 2635.0 µg m−³ with median concentration of 325.0 µg m−³. The strong correlation observed between ambient and exhaled air (r =0.930) demonstrates that exhaled air is a suitable biomarker for evaluating occupational exposure to PERC. |
| Subject: | Química analítica Química ambiental Monitoramento biológico Monitoramento ambiental Marcadores biológicos Cromatografia de gás Espectrometria de massa Extração (Química) Ar Análise Saúde e trabalho |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICX - DEPARTAMENTO DE QUÍMICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.envres.2017.03.025 |
| URI: | http://hdl.handle.net/1843/48956 |
| Issue Date: | 2017 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0013935117305170 |
| metadata.dc.relation.ispartof: | Environmental Research |
| Appears in Collections: | Artigo de Periódico |
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