Use este identificador para citar o ir al link de este elemento:
http://hdl.handle.net/1843/50361| Tipo: | Artigo de Periódico |
| Título: | Alpha-Actinin-3 R577X polymorphism influences muscle damage and hormonal responses after a soccer game |
| Autor(es): | Daniel Barbosa Coelho Eduardo Mendonça Pimenta Izinara Cruz Rosse Christiano Veneroso Guilherme de Azambuja Pussieldi Lenice Kappes Becker Emerson Cruz de Oiveira Maria Raquel Santos Carvalho Emerson Silami Garcia |
| Resumen: | Coelho, DB, Pimenta, EM, Rosse, IC, Veneroso, C, Pussieldi, GDA, Becker, LK, De Oliveira, EC, Carvalho, MRS, and Silami-Garcia, E. Alpha-actinin-3 R577X polymorphism influences muscle damage and hormonal responses after a soccer game. J Strength Cond Res 33(10): 2655–2664, 2019—The purpose of this study was to evaluate indicators of muscle damage and hormonal responses after soccer matches and its relation to alpha-actinin-3 (ACTN3) gene expression (XX vs. RR/RX), considering that the R allele produces alpha-actinin-3 and provides greater muscle strength and power. Thirty players (10 XX and 20 RR/RX) younger than 16 years were evaluated in this study. Blood samples were collected immediately before, after, 2, and 4 hours after the games to assess muscle damage (creatine kinase [CK] and alpha-actin) and hormonal responses (interleukin-6 [IL-6], cortisol, and testosterone). Postgame CK was higher as compared to the pregame values in both groups and it was also higher in the RR/RX (p < 0.05) than in the XX. The concentrations of alpha-actin and IL-6 were similar for both groups and did not change over time. Testosterone was increased after the game only in the RR/RX group (p < 0.05). Cortisol concentrations in group RR/RX were higher immediately after the game than before the game, and 2 and 4 hours after the game the concentration decreased (p < 0.05). The RR and RX individuals presented higher markers of muscle microtrauma and hormonal stress, probably because they performed more speed and power actions during the game, which is a self-regulated activity. From the different responses presented by RR/RX and XX genotypes, we conclude that the genotypic profile should be taken into account when planning training workloads and recovery of athlete. |
| Asunto: | Genética - Expressão Estresse fisiológico Avaliação de desempenho Proteína de ligação Ferimentos e lesões Marcadores biológicos / sangue |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Institución: | UFMG |
| Departamento: | EEF - DEPARTAMENTO DE ESPORTES |
| Tipo de acceso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1519/JSC.0000000000002575 |
| URI: | http://hdl.handle.net/1843/50361 |
| Fecha del documento: | oct-2019 |
| metadata.dc.url.externa: | https://journals.lww.com/nsca-jscr/Fulltext/2019/10000/Alpha_Actinin_3_R577X_Polymorphism_Influences.10.aspx |
| metadata.dc.relation.ispartof: | Journal of Strength and Conditioning Research |
| Aparece en las colecciones: | Artigo de Periódico |
archivos asociados a este elemento:
no existem archivos asociados a este elemento.
Los elementos en el repositorio están protegidos por copyright, con todos los derechos reservados, salvo cuando es indicado lo contrario.