Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/50509| Type: | Artigo de Periódico |
| Title: | Plasma and cerebrospinal fluid levels of cytokines as disease markers of neurologic manifestation in long-term HTLV-1 infected individuals |
| Authors: | Daniela Valadão Freitas Rosa Luiz Alexandre Viana Magno Nathália Cristina Moreira Pereira Luiz Cláudio Ferreira Romanelli Maicon Rodrigues Albuquerque Marina Lobato Martins de Oliveira Anna Barbara de Freitas Carneiro Proietti Rodrigo Nicolato Ana Cristina Simões e Silva Débora Marques de Miranda |
| Abstract: | Aim: The aim of this study is to evaluate the presence of a particular immunological profile in individuals long-term infected with HTLV-1, followed presenting different clinical courses. Materials & methods: Forty-eight individuals were evaluated for 19 cytokines analyzed in cerebrospinal fluid and plasma of patients with HTLV-1 presenting with and without neurological symptoms. Results: Proinflammatory cytokines and the chemokine ligand 11 (ITAC/CXCL11) were increased in individuals with HTLV-1 coursing with neurological symptoms. Conclusion: Different cytokines’ expression profile in the presence of neurological symptoms may help to understand and characterize the progression for severe clinical presentations. |
| Subject: | Antigenos Anticorpos Líquido cefalorraquidiano Paraparesia espástica tropical Infecção por HTLV-1 Citocinas Músculos - Doenças Plasma |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | EEF - DEPARTAMENTO DE ESPORTES MED - DEPARTAMENTO DE PEDIATRIA MED - DEPARTAMENTO DE PSIQUIATRIA E NEUROLOGIA MED - DEPARTAMENTO DE SAÚDE MENTAL |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.2217/bmm-2017-0313 |
| URI: | http://hdl.handle.net/1843/50509 |
| Issue Date: | 2018 |
| metadata.dc.url.externa: | https://www.futuremedicine.com/doi/10.2217/bmm-2017-0313?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed |
| metadata.dc.relation.ispartof: | Biomarkers in Medicine |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.