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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/52322
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dc.creatorChristophertroegerpt_BR
dc.creatorZegeye Abebept_BR
dc.creatorReginald Quansahpt_BR
dc.creatorRajesh Kumar Raipt_BR
dc.creatorSaleem m Ranapt_BR
dc.creatorChhabi Lal Ranabhatpt_BR
dc.creatorSarah e Raypt_BR
dc.creatorMohammad Sadegh Rezaipt_BR
dc.creatorGeorge Mugambage Ruhagopt_BR
dc.creatorSaeid Safiript_BR
dc.creatorJoshua a Salomonpt_BR
dc.creatorBrigette Blackerpt_BR
dc.creatorOlatunde Aremupt_BR
dc.creatorEphrem Tsegay Asfawpt_BR
dc.creatorSolomon Weldegebreal Asgedompt_BR
dc.creatorTesfay Mehari Ateypt_BR
dc.creatorEngi Farouk Attiapt_BR
dc.creatorEuripide Frinel g Arthur Avokpahopt_BR
dc.creatorHenok Tadesse Ayelept_BR
dc.creatorTambe Betrand Ayukpt_BR
dc.creatorKalpana Balakrishnanpt_BR
dc.creatorStephanie r m Zimsenpt_BR
dc.creatorAleksandra Baracpt_BR
dc.creatorIbrahim a Khalilpt_BR
dc.creatorQuique Bassatpt_BR
dc.creatorMasoud Behzadifarpt_BR
dc.creatorMeysam Behzadifarpt_BR
dc.creatorSoumyadeep Bhaumikpt_BR
dc.creatorZulfiqar a Bhuttapt_BR
dc.creatorAli Bijanipt_BR
dc.creatorMichael Brauerpt_BR
dc.creatorAlexandria Brownpt_BR
dc.creatorHamid Yimam Hassenpt_BR
dc.creatorPaulo a m Camargospt_BR
dc.creatorCarlos a Castañeda-orjuelapt_BR
dc.creatorPuja c Raopt_BR
dc.creatorDanny Colombarapt_BR
dc.creatorSara Contipt_BR
dc.creatorAbel Fekadu Dadipt_BR
dc.creatorLalit Dandonapt_BR
dc.creatorRakhi Dandonapt_BR
dc.creatorHuyen Phuc dopt_BR
dc.creatorEleonora Dubljaninpt_BR
dc.creatorMohammad t Hedayatipt_BR
dc.creatorDumessa Edessapt_BR
dc.creatorHajer Elkoutpt_BR
dc.creatorAman Yesuf Endriespt_BR
dc.creatorJackie Caopt_BR
dc.creatorDaniel Obadare Fijabipt_BR
dc.creatorKyle j Foremanpt_BR
dc.creatorMohammad h Forouzanfarpt_BR
dc.creatorNancy Fullmanpt_BR
dc.creatorAlberto l Garcia-basteiropt_BR
dc.creatorBradford d Gessnerpt_BR
dc.creatorMohsen Heidaript_BR
dc.creatorPeter w Gethingpt_BR
dc.creatorRahul Guptapt_BR
dc.creatorTarun Guptapt_BR
dc.creatorGessessew Bugssa Hailupt_BR
dc.creatorDesalegn Tsegaw Hibstupt_BR
dc.creatorNobuyuki Horitapt_BR
dc.creatorOlayinka s Ilesanmipt_BR
dc.creatorMihajlo b Jakovljevicpt_BR
dc.creatorAmr a Jamalpt_BR
dc.creatorAmaha Kahsaypt_BR
dc.creatorBenn Sartoriuspt_BR
dc.creatorAmir Kasaeianpt_BR
dc.creatorSamuel b Albertsonpt_BR
dc.creatorDessalegn Haile Kassapt_BR
dc.creatorYousef Saleh Khaderpt_BR
dc.creatorEjaz Ahmad Khanpt_BR
dc.creatormd Nuruzzaman Khanpt_BR
dc.creatorYoung-ho Khangpt_BR
dc.creatorYun Jin Kimpt_BR
dc.creatorNiranjan Kissoonpt_BR
dc.creatorLuke d Knibbspt_BR
dc.creatorIfedayo Morayo o Adetifapt_BR
dc.creatorSonali Kochharpt_BR
dc.creatorParvaiz a Koulpt_BR
dc.creatorAniruddha Deshpandept_BR
dc.creatorg Anil Kumarpt_BR
dc.creatorRakesh Lodhapt_BR
dc.creatorHassan Magdy Abd el Razekpt_BR
dc.creatorDeborah Carvalho Maltapt_BR
dc.creatorJoseph l Mathewpt_BR
dc.creatorDesalegn Tadese Mengistupt_BR
dc.creatorHaftay Berhane Mezgebept_BR
dc.creatorMiloje Savicpt_BR
dc.creatorKarzan Abdulmuhsin Mohammadpt_BR
dc.creatorMohammed a Mohammedpt_BR
dc.creatorFatemeh Momenihapt_BR
dc.creatorTamer Faragpt_BR
dc.creatorSrinivas Murthypt_BR
dc.creatorCuong Tat Nguyenpt_BR
dc.creatorKatie r Nielsenpt_BR
dc.creatorDina Nur Anggraini Ningrumpt_BR
dc.creatorYirga Legesse Nirayopt_BR
dc.creatorEyal Orenpt_BR
dc.creatorMonika Sawhneypt_BR
dc.creatorJustin r Ortizpt_BR
dc.creatorMahesh papt_BR
dc.creatorMaarten j Postmapt_BR
dc.creatorMostafa Qorbanipt_BR
dc.creatorJun Shept_BR
dc.creatorAziz Sheikhpt_BR
dc.creatorMekonnen Sisay Shiferawpt_BR
dc.creatorMika Shigematsupt_BR
dc.creatorJasvinder a Singhpt_BR
dc.creatorRanjani Somayajipt_BR
dc.creatorJeffrey d Stanawaypt_BR
dc.creatorMuawiyyah Babale Sufiyanpt_BR
dc.creatorTara Ballav Adhikaript_BR
dc.creatorGetachew Redae Tafferept_BR
dc.creatorMohamad-hani Temsahpt_BR
dc.creatorMatthew j Thompsonpt_BR
dc.creatorRuoyan Tobe-gaipt_BR
dc.creatorRoman Topor-madrypt_BR
dc.creatorBach Xuan Tranpt_BR
dc.creatorTung Thanh Tranpt_BR
dc.creatorKald Beshir Tuempt_BR
dc.creatorKingsley Nnanna Ukwajapt_BR
dc.creatorStein Emil Vollsetpt_BR
dc.creatorMohammed Akibupt_BR
dc.creatorJudd l Walsonpt_BR
dc.creatorFitsum Weldegebrealpt_BR
dc.creatorAndrea Werdeckerpt_BR
dc.creatort Eoin Westpt_BR
dc.creatorNaohiro Yonemotopt_BR
dc.creatorMaysaa el Sayed Zakipt_BR
dc.creatorLei Zhoupt_BR
dc.creatorSanjay Zodpeypt_BR
dc.creatorTheo Vospt_BR
dc.creatorMohsen Naghavipt_BR
dc.creatorFaris Hasan al Lamipt_BR
dc.creatorStephen s Limpt_BR
dc.creatorAli h Mokdadpt_BR
dc.creatorChristopher j l Murraypt_BR
dc.creatorSimon i Haypt_BR
dc.creatorRobert c Reinerpt_BR
dc.creatorAyman Al-eyadhypt_BR
dc.creatorNelson Alvis-guzmanpt_BR
dc.creatorAzmeraw t Amarept_BR
dc.creatorYaw Ampem Amoakopt_BR
dc.creatorCarl Abelardo t Antoniopt_BR
dc.date.accessioned2023-04-20T19:26:51Z-
dc.date.available2023-04-20T19:26:51Z-
dc.date.issued2018-
dc.citation.volume1pt_BR
dc.citation.spage1pt_BR
dc.identifier.doi10.1016/s1473-3099(18)30310-4pt_BR
dc.identifier.issn14733099pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/52322-
dc.description.resumoBackground Lower respiratory infections are a leading cause of morbidity and mortality around the world. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, provides an up-to-date analysis of the burden of lower respiratory infections in 195 countries. This study assesses cases, deaths, and aetiologies spanning the past 26 years and shows how the burden of lower respiratory infection has changed in people of all ages.Methods We used three separate modelling strategies for lower respiratory infections in GBD 2016: a Bayesian hierarchical ensemble modelling platform (Cause of Death Ensemble model), which uses vital registration, verbal autopsy data, and surveillance system data to predict mortality due to lower respiratory infections; a compartmental meta-regression tool (DisMod-MR), which uses scientific literature, population representative surveys, and health care data to predict incidence, prevalence, and mortality; and modelling of counterfactual estimates of the population attributable fraction of lower respiratory infection episodes due to Streptococcus pneumoniae, Haemophilus influenzae type b, influenza, and respiratory syncytial virus. We calculated each modelled estimate for each age, sex, year, and location. We modelled the exposure level in a population for a given risk factor using DisMod-MR and a spatio temporal Gaussian process regression, and assessed the effectiveness of targeted interventions for each risk factor in children younger than 5 years. We also did a decomposition analysis of the change in LRI deaths from 2000–16 using the risk factors associated with LRI in GBD 2016.Findings In 2016, lower respiratory infections caused 652 572 deaths (95% uncertainty interval [UI] 586 475–720 612) in children younger than 5 years (under-5s), 1 080 958 deaths (943 749–1 170 638) in adults older than 70 years, and 2 377 697 deaths (2 145 584–2 512 809) in people of all ages, worldwide. Streptococcus pneumoniae was the leading cause of lower respiratory infection morbidity and mortality globally, contributing to more deaths than all other aetiologies combined in 2016 (1 189 937 deaths, 95% UI 690 445–1 770 660). Childhood wasting remains the leading risk factor for lower respiratory infection mortality among children younger than 5 years, responsible for 61·4% of lower respiratory infection deaths in 2016 (95% UI 45·7–69·6). Interventions to improve wasting, household air pollution, ambient particulate matter pollution, and expanded antibiotic use could avert one under-5 death due to lower respiratory infection for every 4000 children treated in the countries with the highest lower respiratory infection burden.Interpretation Our findings show substantial progress in the reduction of lower respiratory infection burden, but this progress has not been equal across locations, has been driven by decreases in several primary risk factors, and might require more effort among elderly adults. By highlighting regions and populations with the highest burden, and the risk factors that could have the greatest effect, funders, policy makers, and programme implementers can more effectively reduce lower respiratory infections among the world’s most susceptible populations.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofTexto & Contexto - Enfermagem-
dc.rightsAcesso Abertopt_BR
dc.subjectGlobal Burden Diseasept_BR
dc.subjectRespiration Infecctionpt_BR
dc.subjectEpidemiologypt_BR
dc.subject.otherSaúde Coletivapt_BR
dc.subject.otherInfecções respiratóriaspt_BR
dc.subject.otherEpidemiologiapt_BR
dc.titleEstimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the global burden of disease study 2016pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi:10.1016/s1473-3099(18)30310-4pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8214-5734pt_BR
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