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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/55703
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dc.creatorLucas Alexandre Santos Marzanopt_BR
dc.creatorFabyolla Lucia Macedo de Castropt_BR
dc.creatorCaroline Amaral Machadopt_BR
dc.creatorJoão Luís Vieira Monteiro de Barrospt_BR
dc.creatorThiago Macedo e Cordeiropt_BR
dc.creatorAna Cristina Simões e Silvapt_BR
dc.creatorAntonio Lucio Teixeirapt_BR
dc.creatorAline Silva de Mirandapt_BR
dc.date.accessioned2023-07-03T20:43:04Z-
dc.date.available2023-07-03T20:43:04Z-
dc.date.issued2022-
dc.citation.volume29pt_BR
dc.citation.issue19pt_BR
dc.citation.spage3392pt_BR
dc.citation.epage3419pt_BR
dc.identifier.doihttp://dx.doi.org/10.2174/0929867328666210923143713pt_BR
dc.identifier.issn1875-533Xpt_BR
dc.identifier.urihttp://hdl.handle.net/1843/55703-
dc.description.resumoTraumatic brain injury (TBI) is a serious cause of disability and death among young and adult individuals, displaying complex pathophysiology including cellular and molecular mechanisms that are not fully elucidated. Many experimental and clinical studies investigated the potential relationship between TBI and the process by which neurons are formed in the brain, known as neurogenesis. Currently, there are no available treatments for TBI’s long-term consequences being the search for novel therapeutic targets, a goal of highest scientific and clinical priority. Some studies evaluated the benefits of treatments aimed at improving neurogenesis in TBI. In this scenario, herein, we reviewed current pre-clinical studies that evaluated different approaches to improving neurogenesis after TBI while achieving better cognitive outcomes, which may consist in interesting approaches for future treatments.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MORFOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofCurrent Medicinal Chemistrypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectTraumatic brain injurypt_BR
dc.subjectNeurogenesispt_BR
dc.subjectHippocampuspt_BR
dc.subjectModelspt_BR
dc.subjectAnimalpt_BR
dc.subjectDentate gyruspt_BR
dc.subjectTherapeuticspt_BR
dc.subject.otherCérebro - Ferimentos e lesõespt_BR
dc.subject.otherNeurologia do desenvolvimentopt_BR
dc.subject.otherHipocampo (Cérebro)pt_BR
dc.subject.otherTerapêuticapt_BR
dc.titlePotential role of adult hippocampal neurogenesis in traumatic brain injurypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.eurekaselect.com/article/118144pt_BR
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