Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/56526| Type: | Artigo de Periódico |
| Title: | Muscle strength and psychiatric symptoms influence health-related quality of life in patients with myasthenia gravis |
| Authors: | Nayara Felicidade Tomazbraz Natalia Pessoa Rocha Érica Leandro Marciano Vieira Izabela Guimarães Barbosa Rodrigo Santiago Gomez Adriana Maria Kakehasi Antonio Lucio Teixeira |
| Abstract: | Myasthenia gravis (MG) is a neuromuscular autoimmune disease characterized by skeletal muscle weakness which can impact motor function and, furthermore, produce negative impact on the health-related quality of life (HRQOL). Objective: To evaluate the predictors for HRQOL in patients with MG. Methods: Eighty patients were evaluated with the MG Foundation of America classification and the MG Composite scale. HRQOL was estimated by the MGQOL15, while anxious and depressive symptoms were evaluated with the Hospital Anxiety and Depression Scale (HAD). Results: The mean age of patients was 41.9 years with mean illness duration of 13.5 years. Almost half of the patients (43.75%) had significant anxiety and more than a quarter (27.50%) had depressive symptoms. Factors that influenced the HRQOL in MG were skeletal muscle weakness and anxiety and depressive symptoms (p < .001 in logistic regres sion model). Conclusion: Anxiety and depressive symptoms, besides motor symptoms, influence HRQOL inMG. Mental health must be a clinical focus in addition to the treatment of somatic symptoms during the course of MG. |
| Subject: | Miastenia Gravis Qualidade de Vida Ansiedade Depressão Debilidade Muscular |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | MED - DEPARTAMENTO DE APARELHO LOCOMOTOR MED - DEPARTAMENTO DE CLÍNICA MÉDICA MED - DEPARTAMENTO DE SAÚDE MENTAL |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.jocn.2018.01.011 |
| URI: | http://hdl.handle.net/1843/56526 |
| Issue Date: | 5-Jan-2018 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0967586817312274?via%3Dihub |
| metadata.dc.relation.ispartof: | Journal of Clinical Neuroscience |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.