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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/56928
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dc.creatorVincenzo Giordanopt_BR
dc.creatorJosé Sérgio Francopt_BR
dc.creatorHilton Augusto Kochpt_BR
dc.creatorPedro José Labronicipt_BR
dc.creatorRobinson Esteves Santos Pirespt_BR
dc.creatorNey Pecegueiro do Amaralpt_BR
dc.date.accessioned2023-07-24T22:16:22Z-
dc.date.available2023-07-24T22:16:22Z-
dc.date.issued2016-
dc.citation.volume43pt_BR
dc.citation.issue4pt_BR
dc.citation.spage276pt_BR
dc.citation.epage285pt_BR
dc.identifier.doihttps://doi.org/10.1590/0100-69912016004010pt_BR
dc.identifier.issn18094546pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/56928-
dc.description.resumoObjective: to evaluate the histologic and morphometric characteristics of bone biopsies of the anterior iliac crest of patients of different age groups. Methods: we studied 30 bone samples from the iliac crest, using brightfield optical microscopy. We divided the samples by donors’ age groups in three groups: Group 1 (n = 10), subjects aged between 25 and 39 years; Group 2 (n = 10), subjects aged between 40 and 64 years; Group 3 (n = 10), individuals aged 65 years and over. We randomly divided the samples into two sets with 15 specimens. In the first study segment (n = 15), we used histological to assess the osteogenic property of the graft, through the analysis of cell reserve in the periosteum, the number of osteocytes in the lacunae and the number of Haversian and Volkmann’s canals. In the second study segment (n = 15), we investigated the morphology of osteoconductive property of the graft, through quantification of the trabecular meshwork (Vv) and trabecular area (Sv). Results: histologically, we observed degeneration of bone occurring with age, characterized by thinning of the periosteum, with gradual replacement of the steogenic layer by fibrous tissue, small amount of Haversian and Volkmann’s canals, osteocyte lacunae voids and fine spongy bone trabeculae, allowing ample medullary space, usually occupied by fat cells and adipocytes. Morphologically, with respect to the quantification of the trabecular meshwork (Vv), we found statistically significant differences between Groups 1 and 3 and between Groups 2 and 3, with reduction of the trabecular meshwork of about 45% in the elderly over 65 years old ; there was no statistically significant difference between Groups 1 and 2. There was also no statistical difference between the Groups regarding Sv. Conclusion: the results of this experiment suggest that, in the elderly (over 65 years old), the osteogenic property of autologous bone graft decreases and the osteoconductive property is compromised.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTORpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRevista do Colégio Brasileiro de Cirurgiões-
dc.rightsAcesso Abertopt_BR
dc.subjectBone Developmentpt_BR
dc.subjectBone/biopsypt_BR
dc.subjectBone/anatomy & histologypt_BR
dc.subjectBone propertiespt_BR
dc.subjectBone Transplantationpt_BR
dc.subject.otherDesenvolvimento Ósseopt_BR
dc.subject.otherBiopsiapt_BR
dc.subject.otherTransplante Ósseopt_BR
dc.titleAge-related changes in bone architecturept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.scielo.br/j/rcbc/a/dNFJDmVFntGXM8B5TqRTMmc/pt_BR
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