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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57582
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dc.creatorCarolina Antunes Magalhãespt_BR
dc.creatorHenrique Cerqueira Guimarãespt_BR
dc.creatorMarco Túlio Gualberto Cintrapt_BR
dc.creatorElvis C. C. Mateopt_BR
dc.creatorMaria Aparecida Bicalhopt_BR
dc.creatorMaria Das Graças Carvalhopt_BR
dc.creatorLirlândia P. Sousapt_BR
dc.creatorPaulo Caramellipt_BR
dc.creatorKarina Braga Gomespt_BR
dc.creatorFernanda M. Campospt_BR
dc.creatorCristina M. G. Lourespt_BR
dc.creatorVanessa Gomes Fragapt_BR
dc.creatorAna Carolina R. de Oliveirapt_BR
dc.creatorAmanda c Chavespt_BR
dc.creatorNatália Pessoa Rochapt_BR
dc.creatorLeonardo Cruz de Souzapt_BR
dc.creatorRaphael d Maiapt_BR
dc.date.accessioned2023-08-07T21:28:11Z-
dc.date.available2023-08-07T21:28:11Z-
dc.date.issued2018-03-09-
dc.citation.volume57pt_BR
dc.citation.issue5pt_BR
dc.citation.spagee77pt_BR
dc.citation.epagee80pt_BR
dc.identifier.doihttps://doi.org/10.1515/cclm-2018-0483pt_BR
dc.identifier.issn1434-6621pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57582-
dc.description.resumoAlzheimer’s disease (AD) is the most frequent cause of dementia, associated with a significant and progressive loss of both cognitive and functional performance [1].Microparticles (MPs) are microvesicles, ranging from 0.1 to 1 µm, released from the cell membrane during its activation and apoptosis. They are involved in cell-cell communication transferring cyto/nuclear proteins, DNA, mRNA and miRNA [2, 3]. Considering that MPs are involved in neuroinflammation and hemostasis, and that levels of several vascular and inflammatory factors were reported to be increased in patients with AD [4], we hypothesized that plasmatic MPs levels (platelet, leukocyte, endothe lial, neuron cell-derived MPs and MPs that express tissue factor [TF]) may be potential biomarkers to AD diagnosis.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofClinical Chemistry and Laboratory Medicine-
dc.rightsAcesso Restritopt_BR
dc.subjectAlzheimer’s diseasept_BR
dc.subjectCognitive Dysfunctionpt_BR
dc.subjectBiomarkerspt_BR
dc.subject.otherDoença de Alzheimerpt_BR
dc.subject.otherDisfunção Cognitivapt_BR
dc.subject.otherBiomarcadorespt_BR
dc.titleBlood neuron cell-derived microparticles as potential biomarkers in Alzheimer’s diseasept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.degruyter.com/document/doi/10.1515/cclm-2018-0483/html-
dc.identifier.orcid0000-0003-3089-655xpt_BR
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