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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/57710
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dc.creatorJúlia Fonseca de Morais Caporalipt_BR
dc.creatorDenise Utsch Gonçalvespt_BR
dc.creatorLudimila Labancapt_BR
dc.creatorLeonardo Dornas de Oliveirapt_BR
dc.creatorGuilherme Vaz de Melo Trindadept_BR
dc.creatorThiago de Almeida Pereirapt_BR
dc.creatorPedro Henrique Diniz Cunhapt_BR
dc.creatorMarina Santos Falci Mourãopt_BR
dc.creatorJosé Roberto Lambertuccipt_BR
dc.date.accessioned2023-08-10T19:54:37Z-
dc.date.available2023-08-10T19:54:37Z-
dc.date.issued2016-04-29-
dc.citation.spage1pt_BR
dc.citation.epage14pt_BR
dc.identifier.doihttps://doi.org/10.1371/journal.pntd.0004672pt_BR
dc.identifier.issn1932-6203pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/57710-
dc.description.resumoBackground:Schistosomal myeloradiculopathy (SMR), the most severe and disabling ectopic form of Schistosoma mansoni infection, is caused by embolized ova eliciting local inflammation in the spinal cord and nerve roots. The treatment involves the use of praziquantel and long term corticotherapy. The assessment of therapeutic response relies on neurological exami nation. Supplementary electrophysiological exams may improve prediction and monitoring of functional outcome. Vestibular evoked myogenic potential (VEMP) triggered by galvanic vestibular stimulation (GVS) is a simple, safe, low-cost and noninvasive electrophysiological technique that has been used to test the vestibulospinal tract in motor myelopathies.This paper reports the results of VEMP with GVS in patients with SMR.Methods:A cross-sectional comparative study enrolled 22 patients with definite SMR and 22 healthy controls that were submitted to clinical, neurological examination and GVS. Galvanic stimulus was applied in the mastoid bones in a transcranial configuration for testing VEMP, which was recorded by electromyography (EMG) in the gastrocnemii muscles.The VEMP variables of interest were blindly measured by two independent examiners.They were the short-latency (SL) and the medium-latency (ML) components of the biphasic EMG wave. Results: VEMP showed the components SL (p = 0.001) and ML (p<0.001) delayed in SMR compared to controls. The delay of SL (p = 0.010) and of ML (p = 0.020) was associated with gait dysfunction.Conclusion: VEMP triggered by GVS identified alterations in patients with SMR and provided additional functional information that justifies its use as a supplementary test in motor myelopathies.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE FONOAUDIOLOGIApt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPLOS Neglected Tropical Diseases-
dc.rightsAcesso Abertopt_BR
dc.subjectSchistosomal myeloradiculopathypt_BR
dc.subjectSchistosoma mansoni infectionpt_BR
dc.subjectGalvanic Vestibular Stimulationpt_BR
dc.subjectVestibular Evoked Myogenic Potentialspt_BR
dc.subject.otherNeuroesquistossomosept_BR
dc.subject.otherEsquistossomose mansonipt_BR
dc.subject.otherPotenciais evocados vestibularespt_BR
dc.titleVestibular-evoked myogenic potential triggered by galvanic vestibular stimulation may reveal subclinical alterations in human t-cell lymphotropic virus type 1-associated myelopathypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://journals.plos.org/plosntds/article/authors?id=10.1371/journal.pntd.0004672pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0544-309Xpt_BR
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