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Tipo:	Artigo de Periódico
Título:	Bioactive Extracts from Annona hypoglauca
Autor(es):	Ricardo C. dos Santos Edvan Alves Chagas Antônio A. de Melo Filho Jacqueline Aparecida Takahashi Ismael Montero Fernandez Pollyana C. Chagas Pedro R. E. Ribeiro Ana Cristina Gonçalves Reis Melo
Resumen:	The aim was to analyze the bioactive potential of hexane and ethanolic extracts from leaves of Annona hypoglauca, Roraima, Brazil, against fungi (Aspergillus flavus and Fusarium proliferatum) and yeast (Candida albicans) and gram-positive bacteria (Staphylococcus aureus and Streptococcus sanguinis) and gramnegative (Escherichia coli and Salmonella typhimurium), antioxidant, antiacetylcholinesterase and cytotoxic activities against Artemia salina, in addition to verify a phytochemical screening. Antioxidant activity of the leaves ethanolic extract 51% to 50 μg mL-1, 16% at the same concentration for the hexane extract. The antiacetylcholinesterase activity presented high variation of the ethanolic extract and 59.76% in the hexane extract. The cytotoxic activity against A. salina was more efficient for the ethanolic extract of the leaves in 27% to 500 μg mL-1. The bioactivity of fungi and yeasts, the ethanolic extract of the leaves of A. hypoglauca showed no inhibition on the fungi F. proliferatum and A. flavus, but the hexane extract inhibited 40.0% and 59.5% on these fungi, respectively. For the inhibition of C. albicans, the extracts hexane (94.5-96.9%) and ethanolic (89.2-92.6%) of the leaves of A. hypoglauca, at all concentrations. Excellent inhibitions on grampositive bacteria were given by the hexane extract in 100% to 500 μg mL-1, but low inhibition for the ethanolic extract for S. aureus in 21.6% to 125 μg mL-1 and for S. Sanguinis 35.5% to 500 μg mL-1. Inhibitions on gramnegative bacteria varied from 26.1% to 42.4% in ethanolic extract and 10.7% to 18.6% in hexanic extract for E. coli; as inhibition of S. typhimurium occurred from 9.3% to 61.1% in ethanolic extract and from 9.1% to 41.2% in hexane extract. Regarding phytochemical screening, the class of compounds observed qualitatively suggests the presence of saponins, flavonoids, triterpenoids and tannins.
Asunto:	Química Compostos bioativos
Idioma:	eng
País:	Brasil
Editor:	Universidade Federal de Minas Gerais
Sigla da Institución:	UFMG
Departamento:	ICX - DEPARTAMENTO DE QUÍMICA
Tipo de acceso:	Acesso Aberto
Identificador DOI:	https://doi.org/10.3303/CET1864049
URI:	http://hdl.handle.net/1843/59496
Fecha del documento:	2018
metadata.dc.url.externa:	https://www.aidic.it/cet/18/64/049.pdf
metadata.dc.relation.ispartof:	Chemical Engineering Transactions
Aparece en las colecciones:	Artigo de Periódico

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