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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59496
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dc.creatorRicardo C. dos Santospt_BR
dc.creatorEdvan Alves Chagaspt_BR
dc.creatorAntônio A. de Melo Filhopt_BR
dc.creatorJacqueline Aparecida Takahashipt_BR
dc.creatorIsmael Montero Fernandezpt_BR
dc.creatorPollyana C. Chagaspt_BR
dc.creatorPedro R. E. Ribeiropt_BR
dc.creatorAna Cristina Gonçalves Reis Melopt_BR
dc.date.accessioned2023-10-16T21:47:30Z-
dc.date.available2023-10-16T21:47:30Z-
dc.date.issued2018-
dc.citation.volume64pt_BR
dc.citation.spage289pt_BR
dc.citation.epage294pt_BR
dc.identifier.doihttps://doi.org/10.3303/CET1864049pt_BR
dc.identifier.issn2283-9216pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59496-
dc.description.resumoThe aim was to analyze the bioactive potential of hexane and ethanolic extracts from leaves of Annona hypoglauca, Roraima, Brazil, against fungi (Aspergillus flavus and Fusarium proliferatum) and yeast (Candida albicans) and gram-positive bacteria (Staphylococcus aureus and Streptococcus sanguinis) and gramnegative (Escherichia coli and Salmonella typhimurium), antioxidant, antiacetylcholinesterase and cytotoxic activities against Artemia salina, in addition to verify a phytochemical screening. Antioxidant activity of the leaves ethanolic extract 51% to 50 μg mL-1, 16% at the same concentration for the hexane extract. The antiacetylcholinesterase activity presented high variation of the ethanolic extract and 59.76% in the hexane extract. The cytotoxic activity against A. salina was more efficient for the ethanolic extract of the leaves in 27% to 500 μg mL-1. The bioactivity of fungi and yeasts, the ethanolic extract of the leaves of A. hypoglauca showed no inhibition on the fungi F. proliferatum and A. flavus, but the hexane extract inhibited 40.0% and 59.5% on these fungi, respectively. For the inhibition of C. albicans, the extracts hexane (94.5-96.9%) and ethanolic (89.2-92.6%) of the leaves of A. hypoglauca, at all concentrations. Excellent inhibitions on grampositive bacteria were given by the hexane extract in 100% to 500 μg mL-1, but low inhibition for the ethanolic extract for S. aureus in 21.6% to 125 μg mL-1 and for S. Sanguinis 35.5% to 500 μg mL-1. Inhibitions on gramnegative bacteria varied from 26.1% to 42.4% in ethanolic extract and 10.7% to 18.6% in hexanic extract for E. coli; as inhibition of S. typhimurium occurred from 9.3% to 61.1% in ethanolic extract and from 9.1% to 41.2% in hexane extract. Regarding phytochemical screening, the class of compounds observed qualitatively suggests the presence of saponins, flavonoids, triterpenoids and tannins.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofChemical Engineering Transactionspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectQuímicapt_BR
dc.subjectCompostos bioativospt_BR
dc.subject.otherQuímicapt_BR
dc.subject.otherCompostos bioativospt_BR
dc.titleBioactive Extracts from Annona hypoglaucapt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.aidic.it/cet/18/64/049.pdfpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8831-1609pt_BR
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