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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/59643
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dc.creatorFlavia Sirotheau Correa Pontespt_BR
dc.creatorLucas Lacerda de Souzapt_BR
dc.creatorCiro Dantas Soarespt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorBruno Augusto Benevenuto de Andradept_BR
dc.creatorHélder Antônio Rebelo Pontespt_BR
dc.creatorDe Abreupt_BR
dc.creatorFernandespt_BR
dc.creatorRodriguespt_BR
dc.creatorDo Nascimentopt_BR
dc.creatorVasconcelospt_BR
dc.creatorCorrêapt_BR
dc.date.accessioned2023-10-18T20:09:57Z-
dc.date.available2023-10-18T20:09:57Z-
dc.date.issued2020-05-
dc.citation.volume49pt_BR
dc.citation.issue5pt_BR
dc.citation.spage549pt_BR
dc.citation.epage557pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.ijom.2019.11.001pt_BR
dc.identifier.issn09015027pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/59643-
dc.description.resumoThe objective was to evaluate the available published data on sinonasal melanoma and analyse its clinical features, treatment modalities, and prognostic factors. An electronic search was undertaken in March 2018 in multiple databases. Eligibility criteria included publications with sufficient clinical, histological, and immunohistochemical information to confirm the diagnosis. Seventy-three publications (439 cases) were included. The lesion was more prevalent in females than in males. There was a higher prevalence in the seventh and eighth decades of life. The lesions mainly presented as epistaxis and commonly involved the nasal cavity. Age (>67.6 years; P=0.0012), primary location (middle turbinate; P=0.0112), disease stage (advanced disease stage; P=0.0026), treatment (radiotherapy; P=0.0111), recurrence (recurrence presented; P=0.0137), and distant metastasis (distant metastasis presented; P=0.0011) were independently associated with a lower survival rate. Recurrence was significantly correlated with age (>67.6 years; P=0.0021), sex (males tended to present a higher recurrence rate than females; P=0.0051), disease stage (stages III and IV presented a higher recurrence rate than stages I and II; P=0.0331), and histological type (amelanotic lesions presented a higher index of recurrence than melanotic lesions; P=0.0095). In conclusion, sinonasal melanoma is a neoplasm with a poor prognosis, presenting a 30.69% possibility of survival after 5 years.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgerypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectnome revista International journal of oral and maxillofacial surgery busca dia 29 do 09 2023 fao clinica assunto Melanoma, Amelanoticpt_BR
dc.subject.otherMelanoma, amelanoticpt_BR
dc.subject.otherRecurrencept_BR
dc.subject.otherParanasal sinusespt_BR
dc.subject.otherSurvivalpt_BR
dc.subject.otherPrognosispt_BR
dc.subject.otherTherapeuticspt_BR
dc.subject.otherNosept_BR
dc.subject.otherEpistaxispt_BR
dc.subject.otherNeoplasm metastasispt_BR
dc.titleSinonasal melanoma: a systematic review of the prognostic factorspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0901502719313992?via%3Dihubpt_BR
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